Category:DMT

DMT Molecule

Recrystallized DMT freebase

Brief overview - What is DMT?

NN-Dimethyltryptamine or DMT for short is an short acting psychedelic entheogen which allows a persons consciousness to voyage into the most incredible dimensions, visions, thoughts and experiences imaginable.

It is without doubt one of the most powerful yet mysterious psychedelics in existence but to classify DMT as merely a drug would be doing it a great injustice as DMT is more a trans dimensional key into places and vistas so profound and awe inspiring that it raises many new questions regarding the nature of reality and our place within it.

DMT exists naturally in every human being and also throughout the plant and animal kingdoms. It occurs naturally in many mammals, marine animals, trees, grasses, flowers and shoots.

DMT is closely related to serotonin, the naturally occurring neurotransmitter that psychedelics affect so widely. The pharmacology of DMT is similar to that of other well-known psychedelics. It affects receptor sites for serotonin in much the same way that LSD, psilocybin, and mescaline do. These serotonin receptors are widespread throughout the body and can be found in blood vessels, muscle, glands, and skin.

There are a number of ways to acquire this entheogen. The first and most difficult way is to have some substantial chemistry knowledge and experience and actually synthesize pure DMT in a laboratory. This a rather tricky and time consuming process and requires access to some rather obscure and hard to acquire chemicals.

The most common and easiest method to acquire DMT is to extract it from the various plant species that contain the compound. The various plants and extraction techniques can be found on this wiki at the extraction teks.

Chemical and physical properties

DMT = N,N-Dimethyltryptamine

Freebase DMT

Appearance: White/Transparent crystals
CAS Registry Number: 61-50-7
Composition: C12H16N2
Molecular Weight: 188.26884 g/mol
Melting point: 44-68°C (Conflicting reports in literature, as mentioned in TIHKAL)
Boiling point: Theoretically 360-380°C
XLogP: 2.0
XLogP3: 2.5 (PubChem)
pKa: 8.68 (Merck Index)
Colorimetric reagent results: Here
Stability/Degradation: Oxidation to DMT N-Oxide (yellow oil) in extended presence of oxygen (specialy in evaporation of dmt-containing solvents with heat and/or fan or generally in prolonged exposure to open air). N-oxide may be reverted back to the parent compound by reduction, as described in the N-Oxide to Freebase Wiki.
Solubility:

Very Soluble in Xylene, Toluene, Limonene, acetone, Isopropyl Alcohol (IPA), methanol, ethanol, Dichloromethane (DCM), chloroform, ether, Butanone (also known as methyl ethyl ketone (MEK)) and butanol.

Soluble in naphtha, hexane, heptane but almost insoluble in these solvents at freezing temperatures

Almost insoluble in water.

DMT N-Oxide

Appearance: Yellow oil
XLogP3: 2
Colorimetric reagent results: Here
Solubility:

Soluble in Xylene, Toluene, Limonene

Slightly soluble in basic water

Insoluble in naphtha

DMT Fumarate

Molecular Weight: 492.608 g/mol
Solubility:

Very soluble in water

Soluble in methanol (~10mg/ml)

Soluble in boiling IPA, Practically insoluble in room temp IPA (~1mg/ml), Insoluble in freeze-cold IPA.

Slightly soluble in ethanol (~5mg/ml)

Insoluble in cold acetone

Insoluble in FASI (Fumaric Acid Saturated IPA)

Insoluble in FASA (Fumaric Acid Saturated Acetone)

Effects

Depending on the dosage, the effects of DMT can range from a multitude of sensations, from bizarre, beautiful and even 'impossible' visions to literally jaw hanging awe as one is propelled into other dimensions of existence where human language and logic cannot even begin to describe or comprehend.

There have been a few attempts to define different levels and types of experience. Psychedelic Monographs and Essays^[1] discusses different levels of a DMT experience.

The Hyperspace Lexicon project is an attempt to create a new vocabulary to try to describe the DMT realm

Pharmacology, toxicity and general safety

For info on DMT safety, please reffer to Health and Safety section

Plants containing DMT

The following is a list of plants known to contain tryptamines. In some, the DMT content may be very small or it may be present together with other potentially unwanted alkaloids. Please research well before extracting from some plant, and be sure you have your desired alkaloids only when bioassaying from a new plant.

Acacia

Acacia auriculiformis

DMT in the leaf (Trout's Notes)

Acacia longifolia

0.2% tryptamine in bark, leaves, some in flowers, phenylethylamine in flowers (Hegnauer 1994)
DMT in plant (Lyceaum)

Acacia maidenii

Bark of A. maidenii contains 0.6% of N-methyltryptamine and DMT in the proportions approx. 2:3 (Fitzgerald & Sioumis 1965)

Acacia melanoxylon

DMT in the bark and leaf, less than 0.02% total alkaloids (Hegnauer 1994)

Acacia mellifera

DMT in the leaf (Trout's Notes)

Acacia nilotica

DMT in the leaf (Trout's Notes)

Acacia obtusifolia

0.4 to 0.5 % DMT/NMT in the dried bark (Csiro 1990)
0.15-0.6% DMT,NMT(2:1)plus trace betacarboline in bark, 0.06-0.2% leaves (Southern Cross University comissioned test 2001)
5-MeoDMT & bufotenine in some loctations (E., Entheogen Review 1995-6; Trout's Notes 2005-10) Is not fast growing in the wild and is under threat of serious overharvesting. Is NOT considered a weed as previously stated here, and will become rarer if wild seed populations exploited further.(Nen, original bioassay subject)

Acacia oerfota

Less than 0.1% DMT in leaf (Ott)

Acacia phlebophylla

0.3% DMT in leaf, NMT (Trout's Notes)

Acacia podalyriaefolia

Tryptamine in the leaf (Trout's Notes)
0.5% to 2% DMT in fresh bark, phenethylamine trace amounts (Hegnauer 1994)

Acacia polyacantha

DMT in leaf (Trout's Notes)

Acacia retinodes

DMT and MMT (www.factorey.ch/Eins.htm)
Less than 0.02% total alkaloids found (Hegnauer 1994)

Acacia rigidula

DMT, NMT, tryptamine, amphetamines, mescaline, nicotine and others (Phytochem. 199

Acacia senegal

DMT, in the leaf

Acacia simplex

DMT and NMT, in the leaf, stem and trunk bark, 0.81% DMT in bark, MMT

Acacia tortilis

DMT, NMT, and other tryptamines

Acacia sieberiana

DMT in the leaf (Trout's Notes)

Anadenanthera

Anadenanthera colubrina

Anadenanthera macrocarpa

Seed pods contain dimethyltryptamine and the seeds bufotenin, bufotenin oxide, and oxide of dimethyltryptamine (GRANIER-DOYEUX 1965)

Anadenanthera_peregrina

Common Reed

Arundo donax

Entire Plant contains 5-MeO-DMT (Shulgin, TIHKAL)Flowers contain DMT, 5-MeO-DMT, and 5-MeO-NMT (Shulgin, TIHKAL)Roots contain DMT, 5-MeO-DMT, 5-MeO-NMT, Bufotenine, bufotenidine, dehydrobufotenidine (Shulgin, TIHKAL)
Plants analyzed in india were found with alkaloids, others from USA where not found to contain DMT based alkaloids (Trout notes)

Desmanthus illinoensis

Root contains DMT - 0.200% (Ott)Root Bark contains DMT - 0.340% (Ott)

Phalaris aquatica

Phalaris arundinacea

Phalaris brachystachys

Phalaris tuberosa

Leaves and seedlings contain DMT, 5-MeO-DMT, and related compounds (Smith 1977)DMT - 0.100% (erowid)5-MeO-DMT - 0.022% (erowid)5-OH-DMT - 0.005% (erowid)

Phragmites australis