25I-NBOH

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Category:
  • Psychedelic
Main effects:
  • Open and closed eye visuals, euphoria, change in perception of time
Side effects:
  • Nausea (possible), vasoconstriction(mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible)
Health risks:
  • paranoia (possible), fear (possible), panic (possible), dystonia (rare), seizure (rare), death (rare)
Important safety remarks:
  • 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
  • Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
  • Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less!


25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen 2C-I. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself.

It was discovered in 2006 by a team at Purdue University.

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