Amor fati's Guide to Juremala

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Note error.png Note: This page tracks the development of Amor fati's Guide to Juremala.[1] The content is to remain accurate as such.


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Mucosahuasca regards the administration of harmaloids to the oral mucosa to activate spice administered in the same manner as a variation to pharmahuasca, as well as to potentiate vaporized spice. It is most commonly used with vaporized spice to lengthen the effects while simultaneously resulting in a more comprehensible experience of a more personable quality. Mucosahuasca is similar to linguahuasca as a more efficient route of administration than oral pharmauasca in that the dosage required is more minimal, irritation to the stomach is not a factor, and the effects do not rely on the state and contents of the digestive system; however, mucosahuasca differs from linguahuasca in that it relies on absorption by the entire oral mucosa, rather than just the sublingual mucosa. The advantage of this less particular route of absorption is that it allows the material being administered to be spread much more thinly and rapidly while preventing dilution by saliva.

Production of Spice Tinctures

For Spice Acetate:

  1. Add ~74mg/mL full-range freebase to the intended dropper bottle.
  2. Dissolve in distilled white vinegar (5% acetic acid), converting to an acetate salt, by shaking vigorously and submerging in a hot-water bath.
  3. Evaporate contents in a food-dehydrator at a temperature below 39°C, with the opened bottle stabilized as close to the fan as possible.
  4. Refill with either vinegar of 50% glycerin/water in order to preserve the contents to prevent spoiling and as a tincture of known concentration.

For Spice Fumarate:

  1. Add ~86mg/mL full-range water-purified fumarates to the intended dropper bottle.
  2. Dissolve in 50% glycerin/water, by shaking vigorously and submerging in a hot-water bath.
  3. The resulting tincture will be ~66mg/mL of DMT and ~2.3mg/drop.

Dosage Character, Amounts and Ratios

It is often found that dosage are easier to measure and administer in the form of a tincture, whereby the number of drops can determine the amounts administered by the known concentration of the tincture.

  • 30mg-40mg worth of full alkaloid spice acetate or fumarate, dry or in a concentrated tincture.
  • >40mg THH to activate sublingual spice, 15mg-30mg to potentiate vaporized spice.
  • 1:1-1:2 of spice to total harmaloids administered to activate sublingual spice.
  • Less harmaloids necessary with use of stronger RIMA's like harmaline.

Maximizing Absorption by the Oral Mucosa

For powders and tinctures alike, it is necessary to maximize surface area contact while minimizing dilution by saliva. The most common manner of sublingual administration is to leave the powder in a pile or the tincture in a puddle and wait (often in some degree of agony) for 5min. while saliva continues to build, but this is unnecessary and inefficient. Spreading the agent as much as possible upon sublingual application will help to reduce burn common in the case of tinctures and to increase surface area contact. Following application, it is best to rapidly spread the agent with the bottom of the tongue to further maximize contact between the agent and the mucous membrane. Saliva must not be allowed to accumulate during administration, as so to avoid this, one should swallow any saliva before it has a chance to accumulate and do so as rapidly as possible. While swallowing the tincture or powder should be avoided as much as possible, with a reduced level of saliva in the mouth, any amount of the active agent that does make it into the throat (oropharynx) will absorb in that portion of the oral mucosa before ever reaching the rest of the digestive track.

  1. Apply thinly to reduce burn and increase surface area contact.
  2. Spread rapidly with the bottom of the tongue to maximize surface area contact and hasten absorption.
  3. Prevent dilution by taking measures to keep the mouth as dry as possible.
    • dilution will result in hampering the contact between the active agent and the mucous membrane, as well as possibly washing it too far into the digestive tract to contribute significantly to the effects of mucosahuasca.
  • To guarantee maximized effectiveness of administration, one should refrain from drinking any fluids too soon after administration.
  • Tinctures should be applied in minimal sets of ~5-10 drops, but each set should be administered as rapidly as possible with the total dosage being administered within 1-2min.


References

  1. amor_fati's Guide to Mucosahuasca WIP Forum Thread[1]