Muscimol and ibotenic acid
Contents
- 1 What are Muscimol and Ibotenic Acid
- 2 Chemical and physical properties
- 3 Effects
- 4 Pharmacology, toxicity and general safety
- 5 Plants containing Muscimol and Ibotenic Acid
- 6 Extraction teks
- 7 Dosages and consumption methods
- 8 History of usage
- 9 Analysis of Muscimol and Ibotenic Acid
- 10 Scientific publications
- 11 Other links of interest
What are Muscimol and Ibotenic Acid
Muscimol and Ibotenic Acid are the main psychoactive compounds present in many mushrooms of the Amanita genus. Muscimol and Ibotenic Acid are dissociatives and selective agonists for the GABAA receptor set, unlike Psilocybin, which is a psychedelic and an agonist for the 5-HT2A receptor set.
Chemical and physical properties
Amanita muscaria contains two main active ingredients, ibotenic acid and its derivative, muscimol. Muscimol is the product of the decarboxylation or drying of ibotenic acid and it is thought that muscimol is as much as ten times as potent as ibotenic acid.
Effects
Pharmacology, toxicity and general safety
Plants containing Muscimol and Ibotenic Acid
Muscimol is produced naturally in the mushrooms Amanita muscaria, Amanita pantherina, and Amanita gemmata, along with muscarine, muscazone, and ibotenic acid. A. muscaria and A. pantherina should be eaten with caution and prepared properly to lessen effects of nausea.; no official deaths from poisoning have been recorded from A. muscaria and A. pantherina. In A. muscaria, the layer just below the skin of the cap contains the highest amount of muscimol, and is therefore the most psychoactive portion.
