Difference between revisions of "Gramine"
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== What is gramine == | == What is gramine == | ||
| − | * Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects | + | * Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects. It is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref> |
== Chemical and physical properties == | == Chemical and physical properties == | ||
Revision as of 11:10, 15 July 2024
What is gramine
- Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects. It is found most commonly in Avena sativa (Oats). [1] [2]
Chemical and physical properties
[Gramine (3-(dimethylaminomethyl)-indole) properties http://wiki.dmt-nexus.me/Psychedelic_Compounds_Chemical_and_Physical_Properties#Gramine]
Extractions
Gramine is not soluble in naphtha or petroleum ether, therefore extractions using these solvents will not contain gramine. It is soluble in ethanol.
Analysis
Gramine and other alkaloid's Rf for TLC and column chromatography
References
- ↑ Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays, Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/
- ↑ https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447
