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What is gramine

  • Gramine is an indole alkaloid present in some plants such as from Phalaris and Arundo spp. It is potentially toxic and therefore extractions from plants that might contain gramine need to be well thought and analysed to make sure there is no gramine.

Chemical and physical properties

[Gramine properties]


To eliminate gramine from extractions, so far there havent been many tested methods but potentially extracting with aliphatic naphtha/hexane/heptane/petroleum ether, and recrystallizing in one of these solvents should get rid of it considering Merck Index indicates it is not soluble in those solvents, as written in the chemical properties link above.


Gramine and other alkaloid's Rf for TLC and column chromatography