Difference between revisions of "25I-NBOH"

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* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.  
 
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.  
 
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
 
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
−
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
+
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
 
}}
 
}}
 
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.  
 
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.  

Revision as of 13:42, 19 April 2014

Safety profile Note error.png
Category:
  • Psychedelic
Main effects:
  • Open and closed eye visuals, euphoria, change in perception of time
Side effects:
  • Nausea (possible), vasoconstriction(mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
Health risks:
  • paranoia (possible), fear (possible), panic (possible), dystonia (rare), seizure (rare), death (rare)
Important safety remarks:
  • 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
  • Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
  • Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less!


25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen 2C-I. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself.

It was discovered in 2006 by a team at Purdue University.

Links

Reference

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