Difference between revisions of "25I-NBOH"
From DMT-Nexus Wiki
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* Open and closed eye visuals, euphoria, change in perception of time | * Open and closed eye visuals, euphoria, change in perception of time | ||
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| − | * Nausea, vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing | + | * Nausea (possible), vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible) |
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| − | * paranoia, fear, | + | * paranoia (possible), fear (possible), panic (possible), dystonia (rare), seizure (rare), death (rare) |
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* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known. | * 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known. | ||
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN! | * Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN! | ||
| − | * Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less! | + | * Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!''' |
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| − | 25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''. | + | '''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''. |
It was discovered in 2006 by a team at Purdue University. | It was discovered in 2006 by a team at Purdue University. | ||
Revision as of 13:31, 19 April 2014
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25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen 2C-I. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself.
It was discovered in 2006 by a team at Purdue University.
Links
- bluelight.org: The Big Dandy 25I-NBOH Thread
- isomerdesign.com: 25I-NBOH
- wikipedia.org: 25I-NBOH
