| Health risks:
|Important safety remarks:
The NBOMe series of chemicals are primarily N-o-methoxybenzyl analogs of the 2C-X family of phenethylamines, and are 5-HT2A (serotonin 2A) receptor agonists. A few are amphetamine analogs. With few exceptions (e.g. mescaline-NBOMe), compounds in this group are active at verly low sub-milligram doses. These chemicals have nearly no history of human use prior to 2010 when they first became available online.
25I-NBOMe effects usually last between 6–10 hours if taken sublingually or bucally (cheek membranes), whereas insufflated usually lasts between 4–6 hours. Both routes of administration can have minor after effects for up to a week.
- strong open and closed eye visuals, including trails, color shifts, brightening, etc.
- mood lift
- mental and physical stimulation
- increase in associative & creative thinking
- increased awareness & appreciation of music
- life-changing spiritual experiences
- feelings of love and empathy
- general change in consciousness
- pupil dilation
- unusual body sensations (facial flushing, chills, goosebumps, body energy)
- change in perception of time, time dilation
- slight increase in heart rate
- yawning, especially when coming up
(likelihood of negative side effects increases with higher doses)
- difficulty focusing
- scrambled communication
- looping, recursive, out of control thinking
- paranoia, fear, and panic
- unwanted and overwhelming feelings
- unwanted life-changing spiritual experiences
- dystonia (rare)
- seizure (rare)
- death (rare)
Toxicity and harm potential
25I-NBOMe is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known. Some pharmacological deaths have been attributed to 25I-NBOMe overdose.
It came to media attention in early 2012 after a cluster of seven non-fatal overdoses with the drug were reported in or around Richmond, Virginia. It is also believed to be the drug that caused a fatal overdose of a teen in East Grand Forks, Minnesota in June 2012 and the death of a 21-year-old man from Little Rock, Arkansas in October 2012.
- 2C-I-NBOMe Fatalities
- 2C-I-NBOMe (25I) Effects
- 2C-I-NBOMe Fatalities
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