Vasicine, Vasicinone and Deoxyvasicin

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Brief overview - What are Vasicine, Vasicinone and Deoxyvasicin?

Chemical and physical properties

Vasicine

(3R)-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol;Peganine

Freebase Vasicine

Vasicine.jpg
  • Composition: C11H12N2O
  • Molecular Weight: 188.22578 g/mol
  • Melting point: 209-211° C (Decomposes) (source)
  • XLogP3: 0.4 (pubchem)
  • Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
  • Solubility: Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info)

Vasicinone

(R)-2,3-dihydro-3-hydroxypyrrolo(2,1-b)quinazolin-9(1H)-one

Freebase Vasicine

Vasicinone.jpg
  • Appearance: White powder
  • Composition: C11H10N2O2
  • Molecular Weight: 202.2093 g/mol
  • Melting point: 203°-204° C (source)
  • XLogP3: 0.4 (pubchem)
  • Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
  • Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicinone can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info

Deoxyvasicine

1,2,3,9-Tetrahydropyrrolo(2,1-b)quinazoline; Deoxypeganin;

Freebase Deoxyvasicine

Deoxyvasicine.jpg
  • Appearance: White to yellow powder
  • Composition: C11H12N2
  • Molecular Weight: 172.22638 g/mol
  • Melting point: 86-87° C (source)
  • XLogP3: 0.4
  • Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
  • Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info)

Effects

Pharmacology, toxicity and general safety

Plants containing vasicine, vasicinone and deoxyvasicine

Extraction teks

Dosages and consumption methods

History of usage

Analysis of vasicine, vasicinone and deoxyvasicine

Scientific publications

Other links of interest