Psilocin and Psilocybin

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Psilocin Molecule
Psilocybin Molecule

Brief overview - What is Psilocin / Psilocybin?

Psilocin (4-Hydroxy-Dimethyltryptamine, or 4-HO-DMT), and Psilocybin (4-Phosphoryloxy-Dimethyltryptamine, or 4-PO-DMT) are the main active alkaloids in "magic mushrooms".

Some psychoactive mushrooms may have other active alkaloids such as Baeocystin, and it is not really sure how different ratios of these alkaloids can affect the experience. Also certain mushrooms have been found with Phenetylamine, which though apparently inactive by itself, may be the reason for some tachycardia and other side-effects in some strains of psilocybin-containing mushrooms (ref Trout's Notes)

There are other active mushrooms, such as Amanita muscaria and pantherina, which do not contain psilocin/psilocybin, but rather ibotenic acid/muscimol. These are completely different substances with different effects, not related to what is mentioned in this entry.

Chemical and physical properties

For solubility, melting point, instabilities etc, check the Psilocybin and the Psilocin Chemical and Physical Properties WIKIs


Pharmacology, toxicity and general safety

Mushrooms containing Psilocin / Psilocybin

Extraction teks

Dosages and consumption methods

Microdose .1-.4g of dried mushrooms Used for mental clarity and alleviation of depression and anxiety in daily life. Dosing every third day is the recommended frequency.

History of usage

Analysis of Psilocin / Psilocybin

Scientific publications

Other links of interest