Difference between revisions of "MXE"
From DMT-Nexus Wiki
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| − | *This is all pure subjective observations and speculation from my history with other Arylcyclohexylamines. | + | ***This is all pure subjective observations and speculation from my history with other Arylcyclohexylamines. |
| − | Mild mu-opiate Receptor Agonist, Moderate Dopamine Receptor Agonist, Mild Sigma Receptor Agonist, Moderate-High NMDA-Receptor Antagonist. | + | -Pharmacology |
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| + | *Mild mu-opiate Receptor Agonist, Moderate Dopamine Receptor Agonist, Mild Sigma Receptor Agonist, Moderate-High NMDA-Receptor Antagonist. | ||
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| + | -Toxicity and Safety | ||
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| + | *Methoxetamine is a very young compound, having only been sold to the open public for around 2 years now. Much care and respect should be taken in handling these unresearched chemicals, dosing should start very low for checking allergies or purity. Remember to titrate your dose up very slowly; monitoring vitals, breathing, and make sure you always have help on hand and nearby. | ||
| + | |||
| + | *As mentioned though Methoxetamine is developed with rational design involved, it is a Ketamine analogue and has it's N-ethyl group chose specifically to increase the over-all potency by weight of the compound. By altering this compound it can be dosed in smaller amounts, greatly reducing the possible risk of interstitial cystitis that may be possible from norketamine in heavy Ketamine users for example. | ||
| + | |||
| + | *This compound was also originally designed for daily use in treatment of the creators Phantom Limb Syndrome/Neurological Pain/Emotional Depression, this does not in any way make it safe to dose daily. Dissociatives have a bad reputation but contrary they are not nearly as toxic as many make them out to be, this said I recommend anyone to dose only once every 2-3 weeks and even then infrequently; we are still dealing with unresearched chemicals though. | ||
| + | |||
| + | *This compound also behaves as a sedative/opioid so precautions should be taken; do not move around too much, do not mix with any sedatives such as benzodiazepines, high dose kava kava and other opioids without proper knowledge of supervision. Your heart rate might also be raised from the DRI effect, take care to not mix with any other stimulants or heavy vasodilators, MAOis. | ||
| + | |||
| + | *Methoxetamine can go well with low doses of natural tryptamines, such as DMT and Psilocybin; in fact they compliment each other very well. Also some low dose phenylethylamines can mix well also but please do not mix unresearched chemicals, this is highly unsafe and dangerous; please respect your mind and body. | ||
== Dosages and consumption methods == | == Dosages and consumption methods == | ||
Revision as of 16:22, 8 November 2011
Contents
Brief overview - What is MXE?
Methoxetamine or 3-MeO-2-Oxo-PCE; is a Dissociative/Psychedelic/Anesthetic.
This compound is the birth child of rational drug design.
Chemical and physical properties
Methoextamine or (RS)2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone
Identifiers
CAS number - 1239943-76-0
ChemSpider - 24721792
Chemical data
Formula - C15H21NO2
Mol. mass - 247.33 g/mol
Effects
Pharmacology, toxicity and general safety
- This is all pure subjective observations and speculation from my history with other Arylcyclohexylamines.
-Pharmacology
- Mild mu-opiate Receptor Agonist, Moderate Dopamine Receptor Agonist, Mild Sigma Receptor Agonist, Moderate-High NMDA-Receptor Antagonist.
-Toxicity and Safety
- Methoxetamine is a very young compound, having only been sold to the open public for around 2 years now. Much care and respect should be taken in handling these unresearched chemicals, dosing should start very low for checking allergies or purity. Remember to titrate your dose up very slowly; monitoring vitals, breathing, and make sure you always have help on hand and nearby.
- As mentioned though Methoxetamine is developed with rational design involved, it is a Ketamine analogue and has it's N-ethyl group chose specifically to increase the over-all potency by weight of the compound. By altering this compound it can be dosed in smaller amounts, greatly reducing the possible risk of interstitial cystitis that may be possible from norketamine in heavy Ketamine users for example.
- This compound was also originally designed for daily use in treatment of the creators Phantom Limb Syndrome/Neurological Pain/Emotional Depression, this does not in any way make it safe to dose daily. Dissociatives have a bad reputation but contrary they are not nearly as toxic as many make them out to be, this said I recommend anyone to dose only once every 2-3 weeks and even then infrequently; we are still dealing with unresearched chemicals though.
- This compound also behaves as a sedative/opioid so precautions should be taken; do not move around too much, do not mix with any sedatives such as benzodiazepines, high dose kava kava and other opioids without proper knowledge of supervision. Your heart rate might also be raised from the DRI effect, take care to not mix with any other stimulants or heavy vasodilators, MAOis.
- Methoxetamine can go well with low doses of natural tryptamines, such as DMT and Psilocybin; in fact they compliment each other very well. Also some low dose phenylethylamines can mix well also but please do not mix unresearched chemicals, this is highly unsafe and dangerous; please respect your mind and body.
Dosages and consumption methods
History of usage
Analysis of MXE
Scientific publications
Other links of interest
http://en.wikipedia.org/wiki/Methoxetamine - Methoxetamine Wiki
http://www.vice.com/read/interview-with-ketamine-chemist-704-v18n2 - Interview with the Creator of Methoxetamine
