Known substance-interactions and their effects

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Error.png WARNING: THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!


Introduction

This article is about the interactions and effects of mixing different entheogens, both with each other and with medicine. Some combinations have a good synergy while others can be a DEADLY combination! Taking any substance carries a high responsibility, please read the WARNING section with great care!

Warning!

THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!

Even though the interactions of certain substances are described here, it is extremely important to be safe at all times! This article is only to give information about interactions and their effects, this article is NOT meant for advice on taking any combination!

Many interactions described here are subjective descriptions, so what is shown here is only an indication on how certain combinations can affect you and how safe they are. Many times those effects are dependent on dose (of each substance), route of administration, timeline of administration, set and setting, your mood, your physical health, your mental health and many other factors.

Psychedelics

DMT

DMT + Harmalas (MAOI)

DMT + Harmalas (MAOI) Information.png

Combination:

OK

Generic information:

Harmalas potentiate and prolong the effects of DMT, while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a MAOI is mandatory.

User descriptions:

House

Positive.png

Oral activation. Potentiation. Slowed-down effect. The two go hand in hand creating a perfect synergy.[1]


DMT + Mushrooms (psilocybin)

DMT + Mushrooms (psilocybin) Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

Another profound synergy that seems to unlock the potential of the mushroom. Either @ peak or after.[2]

The Traveler

Positive.png

Euphoric[3]


DMT + LSD

DMT + LSD Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

Profound synergy. Really adds another more controlled layer to the hyperspatial flow. Highly recommended @ the peak or after the peak.[4]

The Traveler

Positive.png

Euforic, less anxiety. NOTE: best to take the DMT on the trail of the LSD and not on the peak of the LSD.[5]


Harmalas (MAOI)

Mushrooms (psilocybin)

LSD

Mescaline

Iboga

THC

RC's

2C-B

MDAI

MXE

Medicine

SSRI/SSRE

Other

MDMA

MDMA + Harmalas (MAOI)

DMT + Harmalas (MAOI) Information.png

Combination:

BAD IDEA!

Generic information:

Hypertension, Serotonin Syndrome. Death can result out of this combination!

User descriptions:



Ketamine

Kava Kava

Alcohol (Ethanol)

Caffeine

Reference

  1. House in the 'known drug-interactions' thread[1]
  2. House in the 'known drug-interactions' thread[2]
  3. The Traveler in the 'known drug-interactions' thread[3]
  4. House in the 'known drug-interactions' thread[4]
  5. The Traveler in the 'known drug-interactions' thread[5]