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  • Psychedelic, Tryptamine, Synthetic
Main effects:
  • Comparable to other psychedelic tryptamines (e.g. psilocin, 4-aco-DMT): Open/closed-eye visuals, Distorted sense of time, Philosophical insights, Possible ego-loss or contact with non-human entities
Side effects:
  • There are anecdotal reports of body tremors and elevated heart rate. Anxiety, confusion, and motor impairment are among possible side effects as with many psychedelics.

Brief overview - What is 4-HO-DET?

4-HO-DET, also known as 4-hydroxy-N,N-diethyltryptamine, CZ-74, or ethocin, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin and 4-HO-DiPT. 4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog CEY-19 in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

Chemical and physical properties

Metocin or 4-hydroxy-N-methyl-N-ethyltryptamine


CAS number - 22204-89-3

ChemSpider - 8167136

Chemical data

Formula - C14H20N2O

Mol. mass - 232.32 g/mol

Dosages and consumption methods

The doses listed here for ethocin are VERY tentative, and just based on anecdotal reports of this rather scarce tryptamine. Always remember to start low and work your way up with caution.


Threshold - 2-8 mg

Light - 5-10 mg

Common - 8-15 mg

Strong - 10-20 mg

Heavy - 25+ mg