5-MeO-DMT

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Chemical and physical properties

5-methoxy-N,N-dimethyl-tryptamine

Freebase 5-MeO-DMT

• Appearance: Off-white crystals (Sigma Aldrich)
• Composition: C13H18N20
• Molecular Weight: 218.298 g/mol
• Melting Point: 66-67°C, 67-68°C, 69-70°C (Trout's notes and TIHKAL)
• Boiling Point4 : 208-210°C @ 4mm (Hoshino & Shimodaira 1936)
• XLogP: 1.9
• XLogP3: 1.5 (PubChem)
• pKa: 9.3 (Ghosal & Mukherjee 1964)
• Colorimetric reagent results: Here
• Stability: Stable under normal temperatures and pressures. Incompatible with strong oxidizing agents, strong acids (Source)
• Solubility:

Soluble in: Chloroform, ether, DCM, acetone, methanol, ethanol (Trout's notes on simple tryptamines). Soluble in (at least) 20mg/ml 96% ethanol (Source).

Hexane/Naphtha/Pet ether are commonly used to crystallize it (Ott 1993, Espamer et al 1967, Morimoto & Matsumoto 1966, etc) , so it is probably moderately soluble in these solvents.

Practically Insoluble in water (Source)

5-MeO-DMT Hydrochloride

• Melting Point: 145-146°C (TIHKAL)