Chilled Acetone with IPA and Naphtha
Blind placeholder for CIELO (Chrystals In Ethyl-acetate Leisurely OTC). Information has not been verified.
Contents
Introduction
In the CIELO approach, Crystals are formed directly In Ethyl-acetate Leisurely using OTC (over the counter) materials.
The process is simple: aqueous cactus matter is broken down with microwave radiation, saturated with NaCl, made alkaline, and extracted with ethyl acetate. The extract is dried over MgSO4 and salted with citric acid to precipitate mescaline citrate.
Materials
- Three quart jars with leak-proof ethyl-acetate resistant lids
- Food scale to measure weights
- 100g powdered dry cacti
- 80g Ca(OH)2 (lime)
- 300g water
- Microwave
- 80g NaCl (plain table salt)
- 1L ethyl acetate (sometimes labeled "MEK substitute")
- pH paper strips
- 20g MgSO4 (oven dehydrated epson salt)
- Coffee filters
- 300mg of Citric acid (~1/16 of a tsp)
- Xtal scraping tool (e.g. razor blade)
Safety
Ethyl acetate is a natural product in small amounts in some foods and fermented beverages. It is volatile and the smell can be strong. Fume accumulation can be a concern, so work in a well ventilated area and keep lids on as much as possible. The fumes smell sweet and usually dissipate quickly. Read the safety information here, and check your manufacture's MSDS to verify you have ethyl acetate without additives such as methanol. Test all plastic you are planning to use with ethyl acetate and make sure it does not degrade. NEVER pour ethyl acetate down the drain. Not only is solvent in the water an environmental issue, but ethyl acetate can damage PVC pipes. Do not have an open flame anywhere near ethyl acetate. After searching for and reviewing the safety information it is up to you to make an adult personal decision on using ethyl acetate.
These are only good-faith safety tips. They do not guarantee safety. Each adult individual needs to make their personal decisions on how/if to use over the counter chemicals.
Process
1 Paste
Slowly add cactus powder to water while stirring to form a homogeneous paste. Microwave at medium power (~500W) in short 2-5 minute bursts monitoring closely to not boil over and stirring between irradiations. Initial paste will liquefy as the plant matter breaks down and then become a paste again after ~100g of water evaporates. Mix in NaCl (paste will become more runny) and cool. Finally, add Ca(OH)2 to thicken the paste and convert mescaline to its free made form. The ideal paste is both stiff and easy to stir. If needed, adjust consistency by adding more brine (runnier) or lime (stiffer).
2 Pull
Add ~ 400g of ethyl acetate (fill the jar about 3/4 full). Extract for a few hours shaking vigorously every once in a while*. Decant solvent into second jar. About ~ 150g of solvent will remain in to the paste (the pulls are still very efficient despite this). Pull two more times with ~250g ethyl acetate (simply aim to fill the jar to ~3/4 like before). Combined pulls will give about ~750g (~0.9 quarts) of a clear yellow extract. Use pH paper to monitor extraction: green color indicates mescaline presence. By the third pull there should be very little visible green on the pH paper (if any).
*Troubleshooting:
It is important to get the paste consistentcy right. If it is too watery, ethyl acetate will be completely absorbed by the paste and not separate. If it is too dry, it will be hard to mix and the pull won't be as efficient. Plant material is variable and practice helps gets the proper paste consistency. Fortunately, it is possible to make adjustments:
- Too watery: Adding lime will break up the blob and cloudy release solvent. The cloudiness clears up over time.
- Too dry: Simply add water a few ml at a time until paste is easy to mix. Sometimes this is needed in the later pulls.
3 Dry
Add anhydrous MgSO4 to the ethyl acetate extract and swirl well. After at least an hour filter to a new jar. Rinse MgSO4 with ~25ml of fresh ethyl acetate and combine that with the dried extract.
4 Salt
Gently drop citric acid powder into the extract without stirring. Clouds slowly form as the citric acid dissolves by diffusion and settle after a few hours as beautiful citrate xtals**.
As with the pulls, progress in this step can be monitored with pH paper. Color will go from green (alkaline free base present) to orange (salting is complete) to red (excess citric acid in solution). Orange is the target, but no issues are known if over acidifying as long as solvent is not oversaturated and the citric acid can go into solution. One drawback of pH measurements during xtal growth is that the associeted movement may give smaller xtals.
Every 10mg of citric acid (CH3) reacts with enough free base mescaline (M) to precipitate up to 43mg of mescaline citrate:
**Stirring after adding citric acid won't cause any major issues, but xtals will be smaller. Conversely, slowly adding only citric acid may form seed xtals, from which larger xtals grow with subsequent email citric acid addition(s) every few hours. Other dry organic acids may also work and give different crystal qualities (fumaric, malic, oxalic, succinic, ascorbic, lactic, tartaric, etc).
5 Finish
Pour off ethyl acetate into a storage container (solvent can be washed with brine and reused). Use a coffee filter to help pick up any loose xtals. Rinse xtals in both the jar and filter with fresh dry ethyl acetate until yellow color is removed to personal cosmetic satisfaction. Scrape up xtals, and leave them uncovered to evaporate all residual solvent, this is the final product.
Mass spec results are current pending. Hopefully they will show the product is mescaline citrate within measurement sensitivity (already >98% pure) even when not completely white after two rinses. Yields are highly dependent on starting cacti powder and can vary from 0.1% to 5% (0.5% to 1% being common).
