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− | All drugs that can be used [[intranasally]], [[intrarectally]] or [[intravenously]] are in salt form, usually the [[hydrchloric]] salt (HCl). This is because those [[ROA]]'s must use a drug that is water soluble. Salts are all water soluble because they are [[polar]]. If a drug was to be liberated from its salt base, it would be called a freebase, and would then be [[non-polar]].
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− | In [[DMT]] extractions, most of the time inside the plant matter the DMT is produced with a [[tannin]] salt (as opposed to the normal HCl in pharmaceuticals). Tannin is a weak base which can be overpowered in an [[Acid Base]] extraction by other acids such as [[vinegar]] (the most common) or hydrochloric acid/mutraic acid. Tannin can also be subject to the [[Straight to Base]] extraction involving [[NaOH]]/lye.
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− | When the extraction has come to the freebase DMT, it can be pulled by a non-polar substance, usually [[Naptha]].
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