Difference between revisions of "Known substance-interactions and their effects"
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Some report dysphoria at lower doses. I (House) do not find this to be the case I find low doses incredibly euphoric. Higher doses can be known to go beyond human emotions and concepts. Higher doses of DMT are also known to cause strange bodily hallucinations like the feeling that you have stopped breathing, or that your heart has stopped beating. These hallucinations are common and can be countered with conscious relaxation and meditation prior and during the experience. You do not have to submit, per se, but beware that you may have to let go of certain intensities during the experience. It can easily be the most "intense" experience of your life for some people, and this is *NOT* a bad thing! | Some report dysphoria at lower doses. I (House) do not find this to be the case I find low doses incredibly euphoric. Higher doses can be known to go beyond human emotions and concepts. Higher doses of DMT are also known to cause strange bodily hallucinations like the feeling that you have stopped breathing, or that your heart has stopped beating. These hallucinations are common and can be countered with conscious relaxation and meditation prior and during the experience. You do not have to submit, per se, but beware that you may have to let go of certain intensities during the experience. It can easily be the most "intense" experience of your life for some people, and this is *NOT* a bad thing! | ||
+ | ==== DMT + Alcohol ==== | ||
− | + | {{SubstanceInteraction|DMT + Alcohol|#805000|#E0A040|SAFE But...|...| | |
+ | {{UserDescription|House|[[Image:Negative.png]]|I find that combining the spice with a carcinogenic neurotoxin like [[alcohol]] completely negates the experience and masks it with toxic nullification (Yes, I am quite biased)}} | ||
+ | {{UserDescription|The Traveler|[[Image:Negative.png]]|The alcohol did have a negative impact on me. I tried to drink a few beers beforehand to mitigate the anxiety of the [[pharmahuasca]] but that only resulted in dulling down, confusion and nausea.}} | ||
+ | {{UserDescription|Dante|[[Image:Negative.png]]|The Spice doesn't like Alcohol, you'll either wont remember or get a bad vibe.}} | ||
+ | {{UserDescription|Physics131|[[Image:neutral.png]]|Depends on the dose. 1 Beer is ok and helps to reduce pre tripping fear. A bottle of wine before tripping is very uncomfortable and probably dangerous imo.}} | ||
+ | }} | ||
− | {{SubstanceInteraction|DMT + | + | ==== DMT + Benzodiazepines (Xanax) ==== |
− | {{UserDescription| | + | |
+ | {{SubstanceInteraction|DMT + enzodiazepines|#406040|#FF6060|BAD IDEA!|....| | ||
+ | {{UserDescription|stoopkidpzpz|[[Image:negative.png]]|I took 1 MG of Xanax, and felt relaxed in about an hour. | ||
+ | Decided to smoke some enhanced leaf... I smoked A LOT... I re-dosed for about 2 straight hours, 100mg doses each time. | ||
+ | When I was finished I took another 1 MG of Xanax... | ||
+ | A few hours later I became mildly confused, got a SEVERE headache, the worst I have ever had in my life. I had crippling nausea, could barely walk straight.. Ended up projectile vomiting multiple times until I fell asleep..}} | ||
}} | }} | ||
+ | ==== DMT + Cannabis ==== | ||
− | + | {{SubstanceInteraction|DMT + Cannabis|#406040|#60FF60|OK|...| | |
+ | {{UserDescription|House|[[Image:Positive.png]]|OK, although some people don't like it. If you are a daily cannabis smoker it shouldn't be a problem, but if you get anxiety from using [[Cannabis]] occasionally it may be wise not to mix it with [[DMT]].}} | ||
+ | {{UserDescription|Purges|[[Image:neutral.png]]|If I smoke DMT / Changa 1-2 hrs after my last hit of cannabis it is great, if I smoke DMT & Cannabis together it is not so great.}} | ||
+ | {{UserDescription|Entheogenerator|[[Image:neutral.png]]|I always enjoyed DMT + cannabis when I was a daily cannabis smoker. At that time it worked to reduce anxiety and made it easier for me to relinquish control of the situation and allow the DMT to take over. Cannabis does not typically cause anxiety for me when it is used alone. But now that I only smoke cannabis on occasion (5-10 times a year), combining the two tends to cause a lot of anxiety and fear for me. I find that a puff or two of cannabis during the tail end of the DMT afterglow can help with integration, but I can no longer smoke cannabis prior to or at the same time as DMT. }} | ||
+ | }} | ||
− | {{SubstanceInteraction|DMT + | + | ==== DMT + Dissociatives ==== |
− | {{UserDescription| | + | |
− | + | {{SubstanceInteraction|DMT + Dissociatves|#406040|#60FF60|OK|...| | |
− | + | {{UserDescription|Mindlusion|[[Image:Positive.png]]|By far my absolute favourite combination. This experience is equal in intensity as DMT but without the ego loss. An entirely new realm all together where YOUR controller. This can mean many things, its sheer awesomeness with seemingly no downside gives it quite an addictive quality. During my first encounters with this combination I probably went through more DMT in one night then I normally would have in months, maybe a year.}} | |
}} | }} | ||
+ | ==== DMT + Harmalas (MAOI) ==== | ||
+ | |||
+ | {{SubstanceInteraction|DMT + Harmalas (MAOI)|#406040|#60FF60|OK|[[Harmalas]] potentiate and prolong the effects of [[DMT]], while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a [[MAOI]] is mandatory.| | ||
+ | {{UserDescription|House|[[Image:Positive.png]]|Oral activation. Potentiation. Slowed-down effect. The two go hand in hand creating a perfect synergy.}} | ||
+ | }} | ||
==== DMT + LSD ==== | ==== DMT + LSD ==== | ||
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{{UserDescription|House|[[Image:Positive.png]]|Profound synergy. Really adds another more controlled layer to the hyperspatial flow. Highly recommended @ the peak or after the peak.}} | {{UserDescription|House|[[Image:Positive.png]]|Profound synergy. Really adds another more controlled layer to the hyperspatial flow. Highly recommended @ the peak or after the peak.}} | ||
{{UserDescription|The Traveler|[[Image:Positive.png]]|Euphoric, less anxiety. NOTE: For me it's best to take the [[DMT]] on the trail of the [[LSD]] and not on the peak of the LSD.}} | {{UserDescription|The Traveler|[[Image:Positive.png]]|Euphoric, less anxiety. NOTE: For me it's best to take the [[DMT]] on the trail of the [[LSD]] and not on the peak of the LSD.}} | ||
− | {{UserDescription|endlessness|[[Image: | + | {{UserDescription|endlessness|[[Image:Negative.png]]|I didnt like it at all because it felt like LSD acts as an anchor and holds one down, preventing breakthrough}} |
}} | }} | ||
− | |||
==== DMT + MDMA ==== | ==== DMT + MDMA ==== | ||
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{{UserDescription|House|[[Image:Positive.png]]|Euphoric, not as deep of a trip, but there is zero anxiety present which can be useful and awesome in it's own right.}} | {{UserDescription|House|[[Image:Positive.png]]|Euphoric, not as deep of a trip, but there is zero anxiety present which can be useful and awesome in it's own right.}} | ||
}} | }} | ||
− | |||
==== DMT + Mescaline ==== | ==== DMT + Mescaline ==== | ||
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{{UserDescription|House|[[Image:Positive.png]]|Great synergy here. Potentiates the [[mescaline]] and smooths it out.}} | {{UserDescription|House|[[Image:Positive.png]]|Great synergy here. Potentiates the [[mescaline]] and smooths it out.}} | ||
{{UserDescription|The Traveler|[[Image:Neutral.png]]|The mescaline seems to 'dull' the [[DMT]]. So there was not as much effects from smoking the DMT on Mescaline as you would expect.}} | {{UserDescription|The Traveler|[[Image:Neutral.png]]|The mescaline seems to 'dull' the [[DMT]]. So there was not as much effects from smoking the DMT on Mescaline as you would expect.}} | ||
+ | {{UserDescription|Endlessness|[[Image:Negative.png]]|The mescaline seemed to hold the [[DMT]] towards the center of the vision, as if it didnt let it "expand". I saw the DMT visuals curling up, like as if a magnetic/gravitational force didnt let it happen freely. The trip felt weird, it didnt feel 'natural' or 'flowing' to me. Tried it twice in different occasions to similar results and didnt feel like it's a good combination for me}} | ||
}} | }} | ||
+ | ==== DMT + Mushrooms (psilocybin) ==== | ||
− | + | {{SubstanceInteraction|DMT + Mushrooms (psilocybin)|#406040|#60FF60|OK|...| | |
− | + | {{UserDescription|House|[[Image:Positive.png]]|Another profound synergy that seems to unlock the potential of the [[mushroom]]. Either @ peak or after.}} | |
− | {{SubstanceInteraction|DMT + | + | {{UserDescription|The Traveler|[[Image:Positive.png]]|Euphoric}} |
− | {{UserDescription|House|[[Image: | + | {{UserDescription|Endlessness|[[Image:Positive.png]]|When DMT is smoked at the peak or post-peak of mushrooms, there is an extreme synergy that can make it for an incredible experience that can take one very very far! My favourite combo}} |
− | {{UserDescription|The Traveler|[[Image: | + | {{UserDescription|Orion|[[Image:Positive.png]]|Vaporized DMT whilst on mushrooms- Potentiation, intense synergy between the two tryptamines, very strong visuals came thick and fast.}} |
− | {{UserDescription| | + | |
}} | }} | ||
+ | ==== DMT + Suboxone (Buprenorphine + Naloxone) ==== | ||
− | + | {{SubstanceInteraction|DMT + Suboxone|#406040|#60FF60|OK|....| | |
− | + | {{UserDescription|Entheogenerator|[[Image:neutral.png]]|I used DMT several times while on a daily Suboxone maintenance program, and the Suboxone did not have any noticeable effect on the DMT experience. I did not notice any difference between vaporized DMT with Suboxone and vaporized DMT without Suboxone. This may only apply to a person who is undergoing regular buprenorphine treatment and has developed a tolerance to the effects of buprenorphine to the point that it does not produce a "high". If a person without any tolerance to opiates/opioids were to take buprenorphine and then smoke/vaporize DMT, it may dull the effects of DMT to some extent as other opiates/opioids seem to.}} | |
− | {{SubstanceInteraction|DMT + | + | |
− | {{UserDescription| | + | |
− | + | ||
}} | }} | ||
− | |||
=== Harmalas (MAOI) === | === Harmalas (MAOI) === | ||
Side effects include contraindication with certain substances. Make sure you understand interactions with substances before using them! At higher doses users experience nausea and vomiting, but this also isn't necessarily a bad thing, since harmalas are anti-parasitic, purging is often considered cleansing to both the body and the mind. Chest pressure is also common with ayahuasca. Feelings of having something heavy sitting on you. This is normal and if experienced just relax and let it be, it's part of the serpents coil. | Side effects include contraindication with certain substances. Make sure you understand interactions with substances before using them! At higher doses users experience nausea and vomiting, but this also isn't necessarily a bad thing, since harmalas are anti-parasitic, purging is often considered cleansing to both the body and the mind. Chest pressure is also common with ayahuasca. Feelings of having something heavy sitting on you. This is normal and if experienced just relax and let it be, it's part of the serpents coil. | ||
− | |||
==== Harmalas (MAOI) + Caffeine ==== | ==== Harmalas (MAOI) + Caffeine ==== | ||
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{{SubstanceInteraction|Harmalas + 5-MeO-DMT|#805000|#E0A040|OK But...|...| | {{SubstanceInteraction|Harmalas + 5-MeO-DMT|#805000|#E0A040|OK But...|...| | ||
{{UserDescription|rOm|[[Image:Positive.png]]|this could be hard on some metabolism, or dangerous, but IME, a great form of pharmahuasca, more nausea than with N,N-DMT, but also more euphorie.}} | {{UserDescription|rOm|[[Image:Positive.png]]|this could be hard on some metabolism, or dangerous, but IME, a great form of pharmahuasca, more nausea than with N,N-DMT, but also more euphorie.}} | ||
− | {{UserDescription|endlessness|[[Image: | + | {{UserDescription|endlessness|[[Image:Neutral.png]]|Harmalas will significantly increase potency of 5-MeO-DMT. 40-60mg harmaline + 10mg 5-MeO-DMT orally is equivalent to 30-35mg oral 5-MeO-DMT by itself or 10 mg intranasally (see Ott 2001 Note that 35mg by itself was not active dosage to shulgin but was for ott}} |
+ | {{UserDescription|Picatris|[[Image:Negative.png]]|Potentially unsafe combination and health risks due to metabolic issues. For more info search the forum for the thread titled "Does Anyone Here Eat 5-MEO-DMT?".}} | ||
}} | }} | ||
− | |||
==== Harmalas (MAOI) + Kava kava ==== | ==== Harmalas (MAOI) + Kava kava ==== | ||
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{{SubstanceInteraction|Oral Harmalas (MAOI) + Opioids|#604040|#FF6060|BAD IDEA!|Has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure).| | {{SubstanceInteraction|Oral Harmalas (MAOI) + Opioids|#604040|#FF6060|BAD IDEA!|Has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure).| | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Oral Harmalas (MAOI) + L-dopa ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Harmalas + L-dopa|#604040|#FF6060|BAD IDEA!|...| | ||
+ | {{UserDescription|Corpus Callosm|[[Image:Negative.png]]|taking levodopa with MAOIs runs the risk of a hypertensive crisis and levodopa should not be taken for at least 2 weeks after MAOIs; the risk of taking RIMAs (specifically moclobemide) with levodopa is one of increased side effects which include anorexia, nausea, vomiting, agitation, postural hypotension, tachycardia, arrythmias, hypomania, psychosis, depression, headache, flushing, gastrointestinal bleeding, itching, rashes, abnormal involuntary movements. | ||
+ | |||
+ | The thing to recognise about such advice is that some people may not suffer such adverse effects, but there is a significant likelihood of having such a response that it can only be considered wise to avoid such combinations}} | ||
+ | }} | ||
+ | |||
+ | ==== Oral Harmalas (MAOI) + tyrosine ==== | ||
+ | |||
+ | {{SubstanceInteraction|Harmalas + tyrosine|#604040|#FF6060|BAD IDEA!|...| | ||
+ | {{UserDescription|Corpus Callosm|[[Image:Negative.png]]|l-tyrosine taken with MAOIs renders it more likely to be a vasopressor ie cause an elevation in BP. | ||
+ | |||
+ | The thing to recognise about such advice is that some people may not suffer such adverse effects, but there is a significant likelihood of having such a response that it can only be considered wise to avoid such combinationss}} | ||
}} | }} | ||
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+ | ==== Harmalas (MAOI) + Corticosteroids / Prednisone ==== | ||
+ | |||
+ | {{SubstanceInteraction|Oral Harmalas (MAOI) + Corticosteroids / Prednisone|#604040|#FF6060|BAD IDEA!|If you have been on prednisone for more than a couple of weeks you should NEVER stop the treatment abruptly; the dose should always be tapered down to allow your adrenal gland to 'wake up' and start producing glucocorticoids again. | ||
+ | |||
+ | Harmala alkaloids inhibit CYP3a4 which has a role in metabolising prednisone, so the combination can magnify the effects of the steroid including adverse effects on glucose tolerance and lipid profiles.).| | ||
+ | }} | ||
=== Mushrooms (psilocybin) === | === Mushrooms (psilocybin) === | ||
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{{SubstanceInteraction|Mushrooms + Harmala (MAOI)|#805000|#E0A040|SAFE But|...| | {{SubstanceInteraction|Mushrooms + Harmala (MAOI)|#805000|#E0A040|SAFE But|...| | ||
{{UserDescription|House|[[Image:Positive.png]]|I personally love the harmala + mushrooms synergy, but some have noted that the harmalas potentiate the mushrooms very much and have had rough trips! If you want to experiment with this combo, start low and work your way up!}} | {{UserDescription|House|[[Image:Positive.png]]|I personally love the harmala + mushrooms synergy, but some have noted that the harmalas potentiate the mushrooms very much and have had rough trips! If you want to experiment with this combo, start low and work your way up!}} | ||
+ | |||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|I tried this combo at a fairly high dose, it GREATLY potentiated the effects.. And I absolutely loved it, quite more then the intensity I was looking for. The intensity gets tiresome on the tail-end when your exhausted and hoping to sleep. If you try this combo, its great, just be prepared to trip for a LONG time.}} | ||
+ | |||
+ | {{UserDescription|pitubo|[[Image:Positive.png]]|Very interesting modification of the mushroom experience. Be careful to use only half or even less of your regular dose of mushrooms when combining with harmalas. Potentiation two- or threefold is to be expected even on moderate doses (100-125mg) of harmalas. Especially stronger doses of harmalas will intensify and prolong the mushroom trip far beyond what it would otherwise do. What I personally appreciate very much from this combination is the extended afterglow that keeps me in a special mood after the mushroom's effect wears out. }} | ||
}} | }} | ||
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{{UserDescription|Bedazzle|[[Image:Negative.png]]|Tends to dull the trip, slower than cocaine however. Also, people tend to get negative from this combo. One might hypothesize that alcohol tends to turn the trip in a darker direction.}} | {{UserDescription|Bedazzle|[[Image:Negative.png]]|Tends to dull the trip, slower than cocaine however. Also, people tend to get negative from this combo. One might hypothesize that alcohol tends to turn the trip in a darker direction.}} | ||
{{UserDescription|Dante|[[Image:Negative.png]]|Bad idea, high chances to end up puking and feeling miserable.}} | {{UserDescription|Dante|[[Image:Negative.png]]|Bad idea, high chances to end up puking and feeling miserable.}} | ||
+ | {{UserDescription|Frankycou|[[Image:Negative.png]]|This is potentially very unsafe! some type of mushroom are known to develop poison when mixed with alcohol. This is very rough information that I am reporting since I don't remember the exact text and source but basically I read from a reputed source that some types are EXTREMLY BAD to mix and should be avoided at all cost.}} | ||
}} | }} | ||
− | |||
==== Mushrooms + Alcohol + Cocaine + MDMA==== | ==== Mushrooms + Alcohol + Cocaine + MDMA==== | ||
− | {{SubstanceInteraction|Mushrooms + Alcohol + Cocaine + MDMA|#604040|#FF6060|BAD IDEA!| | + | {{SubstanceInteraction|Mushrooms + Alcohol + Cocaine + MDMA|#604040|#FF6060|BAD IDEA!|...| |
− | {{UserDescription|Dante|[[Image:Negative.png]]|Bad bad idea. I took the MDMA, Coke and Alcohol at the end of a Shrooms trip. Anxiety and profound guilt were felt in my whole body | + | {{UserDescription|Dante|[[Image:Negative.png]]|Bad bad idea. I took the MDMA, Coke and Alcohol at the end of a Shrooms trip. Anxiety and profound guilt were felt in my whole body}} |
}} | }} | ||
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{{UserDescription|endlessness|[[Image:Positive.png]]|Strong synergy with Psilocybe mushrooms.}} | {{UserDescription|endlessness|[[Image:Positive.png]]|Strong synergy with Psilocybe mushrooms.}} | ||
{{UserDescription|Dante|[[Image:neutral.png]]|I took the Mushrooms while coming down from the LSD and I didn't feel any effect whatsoever. (EDIT: You probably have to take lots of Shrooms to fight the tollerance)}} | {{UserDescription|Dante|[[Image:neutral.png]]|I took the Mushrooms while coming down from the LSD and I didn't feel any effect whatsoever. (EDIT: You probably have to take lots of Shrooms to fight the tollerance)}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:neutral.png]]|I haven't experimented enough with this combination to say for sure. Only very small doses, and they were kind of hazy.}} | ||
+ | {{UserDescription|Solar Garlic|[[Image:Positive.png]]|This is one of my favorite combinations for tantric dance. I take around a gram of mushrooms right at peak. Fantastic synergy.}} | ||
}} | }} | ||
− | |||
==== LSD + MDMA ==== | ==== LSD + MDMA ==== | ||
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{{UserDescription|ChaoticMethod|[[Image:Positive.png]]|MDMA and LSD together is one of the most amazing synergy in terms of dancefloor experience...}} | {{UserDescription|ChaoticMethod|[[Image:Positive.png]]|MDMA and LSD together is one of the most amazing synergy in terms of dancefloor experience...}} | ||
{{UserDescription|Dante|[[Image:Positive.png]]|The only time I did it, I took the LSD a while after the MDMA. Everything was very smooth and shiny. Great dancing combo!}} | {{UserDescription|Dante|[[Image:Positive.png]]|The only time I did it, I took the LSD a while after the MDMA. Everything was very smooth and shiny. Great dancing combo!}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]| | ||
+ | MDMA removes any negative experiences I feel with LSD. POWERFULLY beautiful combination! All aesthetics are increased 10x, music is beautiful and flowing, playing music is amazing, dancing is amazing. Cuddling, hugging, telling people you love them... yes, this is a winner.}} | ||
}} | }} | ||
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{{UserDescription|The Traveler|[[Image:Negative.png]]|I almost never use [[cannabis]], I wanted to use the cannabis versus the stimulation of the LSD. It gave me more visuals but it also made me dizzy. Overall I did not like it.}} | {{UserDescription|The Traveler|[[Image:Negative.png]]|I almost never use [[cannabis]], I wanted to use the cannabis versus the stimulation of the LSD. It gave me more visuals but it also made me dizzy. Overall I did not like it.}} | ||
{{UserDescription|Universecannon|[[Image:Positive.png]]|Definitely has led to a bunch of paranoia at times (I'm prone to that with weed alone though) but if combined carefully it can be totally worth it although i never do it anymore (no lsd). If a large amount is smoked at the peak-especially if i have a low tolerance- then it can really catapult the experience into a sort of out of body type thing with full blown 3-d immerse visions, IME}} | {{UserDescription|Universecannon|[[Image:Positive.png]]|Definitely has led to a bunch of paranoia at times (I'm prone to that with weed alone though) but if combined carefully it can be totally worth it although i never do it anymore (no lsd). If a large amount is smoked at the peak-especially if i have a low tolerance- then it can really catapult the experience into a sort of out of body type thing with full blown 3-d immerse visions, IME}} | ||
− | {{UserDescription|Dante|[[Image: | + | {{UserDescription|Dante|[[Image:neutral.png]]|It gives a bit of anxiety, although the effect of LSD is potentiated for a little while. Be aware, it's very hard to roll a spliff while tripping }} |
+ | {{UserDescription|Poppyfire|[[Image:Positive.png]]|Cannabis mellows out some of the more intense surges of body energy during the come-up of the LSD trip, which on their own can be unnerving at high doses. The combination of cannabis and LSD has been a favourite of mine for years, as the cannabis induces a calm state of mind, plus I personally don't enjoy taking LSD completely sober. }} | ||
+ | }} | ||
+ | |||
+ | ==== LSD + Cannabis + Tobacco==== | ||
+ | |||
+ | {{SubstanceInteraction|LSD + Cannabis + Tobacco|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|I mostly smoke spliffs, but I find spliffs (a 50/50 mix of cannabis and tobacco) To be quite pleasant at all periods of the LSD comeup. Usually my physical form is quite shakey and or cold during the LSD comeup, and cannabis warms me up and calms down any tension or shakiness. Spliffs induce a deep trance state for me, very pleasant.}} | ||
}} | }} | ||
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{{UserDescription|The Traveler|[[Image:Negative.png]]|The MXE potentiates the [[LSD]] effects with more visuals but it also significantly alters motor function to the point of immobility at high doses.}} | {{UserDescription|The Traveler|[[Image:Negative.png]]|The MXE potentiates the [[LSD]] effects with more visuals but it also significantly alters motor function to the point of immobility at high doses.}} | ||
{{UserDescription|Pandora|[[Image:Positive.png]]|Radical and profound potentiation/synergy. 12+ hour trip and much longer to sleep. I really love the synergy of LSD+MXE but I'm the kind of person who naturally chills during a trip, so being pancaked by effects is just an extra plus for me.}} | {{UserDescription|Pandora|[[Image:Positive.png]]|Radical and profound potentiation/synergy. 12+ hour trip and much longer to sleep. I really love the synergy of LSD+MXE but I'm the kind of person who naturally chills during a trip, so being pancaked by effects is just an extra plus for me.}} | ||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|I have tried this combination many times, but only at high doses of MXE, I loved this combination, it intensified and increased the depth and power of the dissociated 'hole' while making it easier to bring back more from the experience. The only negative effects Ive felt is the dissociated 'whobblies' that last for an hour or two after the hole, which can be annoying while trying walk around on LSD. In my experience, it is best taken early in the LSD trip, when the effects subside you are usually at the LSD peak, this also seems to ease any anxiety. (I would also like to mention I am quite mobile at high doses of MXE while on LSD, only after mobility can be hindered by the drunken like 'whobblies')}} | ||
}} | }} | ||
+ | |||
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{{SubstanceInteraction|LSD + Amphetamines|#805000|#E0A040|Depends|...| | {{SubstanceInteraction|LSD + Amphetamines|#805000|#E0A040|Depends|...| | ||
{{UserDescription|ChaoticMethod|[[Image:neutral.png]]|Somewhat safe but...Makes the LSD less visual and a bit more difficult to handle mentally because of the stress caused by the stimulants. It can be an interesting mix if partying but I would try to avoid it if possible. At least try to get pharmaceutical grade stimulants and not dirty street pills.}} | {{UserDescription|ChaoticMethod|[[Image:neutral.png]]|Somewhat safe but...Makes the LSD less visual and a bit more difficult to handle mentally because of the stress caused by the stimulants. It can be an interesting mix if partying but I would try to avoid it if possible. At least try to get pharmaceutical grade stimulants and not dirty street pills.}} | ||
+ | {{UserDescription|doubletrouble|[[Image:Negative.png]]|Took 10mg dextroamphetamine on the comedown from the LSD once. got severe spasms and "lightning flashes" and zaps through my brain and whole body. It was extremely uncomfortable. LSD in itself is a pretty potent stimulant. Just stupid to mix with another}} | ||
}} | }} | ||
− | |||
==== LSD + Harmalas (MAOI) ==== | ==== LSD + Harmalas (MAOI) ==== | ||
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{{UserDescription|House|[[Image:Positive.png]]|You MUST make sure you have pure LSD, however! You do not want to mix harmala (RIMA, MAOI) with an unknown drug laid on blotter. It's great taken with a dose or taken after the dose has kicked in, as the vasodilation of the harmala counters the vasoconstriction of the LSD.}} | {{UserDescription|House|[[Image:Positive.png]]|You MUST make sure you have pure LSD, however! You do not want to mix harmala (RIMA, MAOI) with an unknown drug laid on blotter. It's great taken with a dose or taken after the dose has kicked in, as the vasodilation of the harmala counters the vasoconstriction of the LSD.}} | ||
{{UserDescription|Enoon|[[Image:Neutral.png]]|Super strong synergy, stronger than usual visuals, visions, OBE, but also nausea, imobility and substatial amount of apprehension}} | {{UserDescription|Enoon|[[Image:Neutral.png]]|Super strong synergy, stronger than usual visuals, visions, OBE, but also nausea, imobility and substatial amount of apprehension}} | ||
− | |||
{{UserDescription|endlessness|[[Image:Positive.png]]|Strong synergy/potentiation, first timers should take very small doses to see how they react and only raise gradually.}} | {{UserDescription|endlessness|[[Image:Positive.png]]|Strong synergy/potentiation, first timers should take very small doses to see how they react and only raise gradually.}} | ||
− | + | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|I must admit I'm a bit of a Harmala "fiend". I love them and I see no negative applications to them, pretty much, as long as you are physically safe. They potentiate the visuals of LSD, get rid of the shakes and nervousness, help me emotionally sort through things and make me warm and content and happy. This is a WINNING combination, especially with chocolate caffeine or spliffs. all very good in my books. Great for meditation, dancing, writing, drawing, or playing music.}} | |
+ | }} | ||
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{{UserDescription|House|[[Image:negative.png]]|Doesn't make sense to me to combine a CNS depressant with the brilliant effects of LSD.}} | {{UserDescription|House|[[Image:negative.png]]|Doesn't make sense to me to combine a CNS depressant with the brilliant effects of LSD.}} | ||
{{UserDescription|Dante|[[Image:Positive.png]]|Great and jolly, but it makes the trip a bit blurry and less powerful. Don't over do it, your liver wont appreciate it!.}} | {{UserDescription|Dante|[[Image:Positive.png]]|Great and jolly, but it makes the trip a bit blurry and less powerful. Don't over do it, your liver wont appreciate it!.}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:neutral.png]]|I don't enjoy alcohol in general, so I'm slightly bias. When I was younger (15-16) I would shotgun beers on LSD and that was quite nice, but any hard alcohol combined with LSD turns you into a flailing, falling idiot apologizing for making such a big mess.}} | ||
+ | {{UserDescription|doubletrouble|[[Image:Positive.png]]|Amazing combo for dancing and having pure fun. Makes the come-up a bit easier too. For deeper tripping, not so much though.}} | ||
}} | }} | ||
+ | |||
+ | ==== LSD + GHB==== | ||
+ | |||
+ | {{SubstanceInteraction|LSD + GHB|#805000|#E0A040|Depends|...| | ||
+ | {{UserDescription|Shadowman-x|[[Image:neutral.png]]|I don't have enough concrete experience with this combination, but I haven't experienced negative interactions the few times I have done them. the GHB is very warm and mellow, although a bit of nausea or headache or spinny-ness can occur at higher doses, if everything is kept moderate it is much more pleasant than alcohol, although not quite as pleasant as MDMA.}} | ||
+ | }} | ||
+ | |||
Line 273: | Line 338: | ||
− | Mescaline is a phenethylamine that does not have an amphetamine group on the molecule, unlike MDMA. This allows it to be able to be used with harmalas without contraindication. | + | Mescaline is a phenethylamine that does not have an amphetamine group on the molecule, unlike MDMA. This allows it to be able to be used with harmalas without contraindication. A very gentle and long lasting psychedelic with great empathic and stimulating properties. |
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{{UserDescription|Dante|[[Image:positive.png]]|Nice combo, but it wasn't enough to understand its effects.}} | {{UserDescription|Dante|[[Image:positive.png]]|Nice combo, but it wasn't enough to understand its effects.}} | ||
}} | }} | ||
− | |||
=== Iboga === | === Iboga === | ||
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{{SubstanceInteraction|Iboga + LSD|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Iboga + LSD|#406040|#60FF60|OK|...| | ||
− | {{UserDescription|House|[[Image:Positive.png]]|LSD becomes much more potent after Iboga and I would suggest taking it sometime between 1-7 days after taking a low dose of Iboga. For me I find that the LSD really puts the teachings of the Iboga into perspective. Be careful though, there is a | + | {{UserDescription|House|[[Image:Positive.png]]|LSD becomes much more potent after Iboga and I would suggest taking it sometime between 1-7 days after taking a low dose of Iboga. For me I find that the LSD really puts the teachings of the Iboga into perspective. Be careful though, there is a definite potentiation.}} |
{{UserDescription|rOm|[[Image:negative.png]]|very challenging in my experience so the LSD was probably very high (vial wash) with loads of noribogaine (2 grams RB every days for four to five days) in the system. I personnally wouldn't recommend it.}} | {{UserDescription|rOm|[[Image:negative.png]]|very challenging in my experience so the LSD was probably very high (vial wash) with loads of noribogaine (2 grams RB every days for four to five days) in the system. I personnally wouldn't recommend it.}} | ||
}} | }} | ||
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{{UserDescription|House|[[Image:Positive.png]]|This is a pretty classic and noteable synergy that many people love. The K takes you very deep into yourself, and away from yourself at the same time.}} | {{UserDescription|House|[[Image:Positive.png]]|This is a pretty classic and noteable synergy that many people love. The K takes you very deep into yourself, and away from yourself at the same time.}} | ||
{{UserDescription|Purges|[[Image:Positive.png]]|OK. Similar to the 2CB combo, be careful, both of these drugs have a tendency to be a bit mind bending, and in combo, expect it to get wild!}} | {{UserDescription|Purges|[[Image:Positive.png]]|OK. Similar to the 2CB combo, be careful, both of these drugs have a tendency to be a bit mind bending, and in combo, expect it to get wild!}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|LSD + Ketamine is definitely a strange combination. In my experience it lends itself to meditation because alot of the time the mind is too befuddled to properly draw a train of thought. I find this combination quite inarticulating, it's one of the few drug interactions that make me a bit of a "dumbass", and just puddle me on the floor. Lower doses of ketamine + lsd are good for dancing, higher doses, for trancing.}} | ||
}} | }} | ||
Line 432: | Line 497: | ||
{{UserDescription|House|[[Image:Positive.png]]|DMT on Ketamine is out of this world stellar. The dissociative properties of ketamine completely eliminate any anxiety present, and the two work together to take you deep into whatever it is that we are...}} | {{UserDescription|House|[[Image:Positive.png]]|DMT on Ketamine is out of this world stellar. The dissociative properties of ketamine completely eliminate any anxiety present, and the two work together to take you deep into whatever it is that we are...}} | ||
{{UserDescription|endlessness|[[Image:Positive.png]]|Some people suggest ketamine may smooth the entry int tryptamine space and some report incredible experiences. Special care is needed with ketamine due to it's potentially addictive nature and due to being dissociative/anaesthetic and increased risks of physical accidents. Justin Case's best results have been reported when k dose is kept low and tryptamine dose is solid but not excessive.}} | {{UserDescription|endlessness|[[Image:Positive.png]]|Some people suggest ketamine may smooth the entry int tryptamine space and some report incredible experiences. Special care is needed with ketamine due to it's potentially addictive nature and due to being dissociative/anaesthetic and increased risks of physical accidents. Justin Case's best results have been reported when k dose is kept low and tryptamine dose is solid but not excessive.}} | ||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|This combination is grandeur, extremely powerful. I agree with both House and Endlessness, especially about the addictive part. Extensive use of the this combination and other DMT + Dissociatives, seems to make a preexisting addiction worse. It's a lot of strain on ones psyche to abuse this combo.) }} | ||
}} | }} | ||
− | |||
− | |||
==== Ketamine + LSD + DMT ==== | ==== Ketamine + LSD + DMT ==== | ||
{{SubstanceInteraction|Ketamine + LSD + DMT|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Ketamine + LSD + DMT|#406040|#60FF60|OK|...| | ||
− | {{UserDescription|House|[[Image:Positive.png]]|Throwing | + | {{UserDescription|House|[[Image:Positive.png]]|Throwing DMT into the mix is just that much more powerful.}} |
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|^ What House said.}} | ||
}} | }} | ||
− | |||
==== Ketamine + MDMA ==== | ==== Ketamine + MDMA ==== | ||
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{{UserDescription|Dante|[[Image:negative.png]]|Some people love it, I don't. I don't like small bumps of K, so when I take it, it always end up taking over all the rest.}} | {{UserDescription|Dante|[[Image:negative.png]]|Some people love it, I don't. I don't like small bumps of K, so when I take it, it always end up taking over all the rest.}} | ||
}} | }} | ||
− | + | ||
+ | Trippy as fook. So fun , but dangerous at high quantities of MDMA and Ket due to their different natures being sedative and stimulant. But extra trippy more like a lucid dream than a trip in my opinion | ||
==== Ketamine + Alcohol ==== | ==== Ketamine + Alcohol ==== | ||
Line 456: | Line 521: | ||
}} | }} | ||
+ | |||
+ | Alcohol makes ketamine stronger or more potent to the nervous system making it easier to enter the k hole. Its fun but definitely bad for the cardiovascular side of things. | ||
===Salvia Divinorum=== | ===Salvia Divinorum=== | ||
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{{SubstanceInteraction|Salvia + DMT|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Salvia + DMT|#406040|#60FF60|OK|...| | ||
− | {{UserDescription| | + | {{UserDescription|Mysmelf|[[Image:Positive.png]]|OK. can be extremely disturbing though or unbelievably profound and real.}} |
}} | }} | ||
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{{SubstanceInteraction|Salvia + Changa + Cannabis|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Salvia + Changa + Cannabis|#406040|#60FF60|OK|...| | ||
− | {{UserDescription| | + | {{UserDescription|Mysmelf|[[Image:Positive.png]]|This is probably my favorite mix. I've had some of my deepest experiences mixing these three including one with multiple breakthroughs one on top of the other cascading deeper with a new universe created and destroyed each time.}} |
}} | }} | ||
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{{SubstanceInteraction|Salvia + Cannabis|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Salvia + Cannabis|#406040|#60FF60|OK|...| | ||
− | {{UserDescription| | + | {{UserDescription|Mysmelf|[[Image:Positive.png]]|This is a very therapeutic anesthetic. This kills pain very well and leaves me in a dreamy visionary state without the mind warping dissociating effects that salvia has on its own. As long as you don't go heavy on the salvia! }} |
{{UserDescription|tigerstrike92|[[Image:Positive.png]]|Good! Great way to take the edge off of the pre-flight anxiety for salvia, which can be pretty rough at times.}} | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|Good! Great way to take the edge off of the pre-flight anxiety for salvia, which can be pretty rough at times.}} | ||
}} | }} | ||
Line 501: | Line 568: | ||
}} | }} | ||
+ | |||
+ | ==== 2C-B + MDMA ==== | ||
+ | |||
+ | {{SubstanceInteraction|2C-B + MDMA|#406040|#60FF60|OK, but|...| | ||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|Shulgin's classic combo. 2C-B is best taken 1.5-2h after dosing the MDMA! It smooths out the comedown, and the MDMA potentiates the 2C-B and makes for a powerful and unique empathogenic and psychedelic experience. But keep the MDMA dose low! Let 2C-B really bring the magic, increasing the MDMA dose only makes for a worse comedown and possible toxic effects!}} | ||
+ | }} | ||
==== MDMA + 2CB + K + Cannabis ==== | ==== MDMA + 2CB + K + Cannabis ==== | ||
Line 508: | Line 581: | ||
}} | }} | ||
+ | Had this mix over the space of 12 hours at a music festival , after coming out of the k hole after forgetting i had ingested 2cb , had a hell ride in the medical tent for hours. Wouldnt recommend this mix. | ||
=== 2C-I === | === 2C-I === | ||
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{{SubstanceInteraction|5-MeO-DALT + MXE|#805000|#E0A040|Depends|...| | {{SubstanceInteraction|5-MeO-DALT + MXE|#805000|#E0A040|Depends|...| | ||
− | {{UserDescription|gory dkalz|[[Image: | + | {{UserDescription|gory dkalz|[[Image:negative.png]]|While on ~50mg 5-MeO-DALT orally I did a little test bump of 15 mg MXE insufflated and within minutes felt my heart rate go up and felt very dizzy. Thought that I had finally done it and mixed the wrong stuff and I would have to go to the ER but it stopped escalating and I just waited it out.}} |
}} | }} | ||
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}} | }} | ||
+ | |||
+ | === AM-2201 === | ||
+ | |||
+ | ==== AM-2201 + MDMA ==== | ||
+ | |||
+ | {{SubstanceInteraction|AM-2201 + MDMA|#805000|#E0A040|Depends|...| | ||
+ | {{UserDescription|Orion|[[Image:Negative.png]]|Can be VERY hallucinogenic, only smoke a little! Bizarre and realistic and gory hallucinations (man with half a leg bleeding allover the place!) are possible, voices become distorted and merged and speak impossible ridiculous things. The hallucination is short lived.}} | ||
+ | }} | ||
=== MDAI === | === MDAI === | ||
+ | |||
+ | ==== MDAI + DMT ==== | ||
+ | |||
+ | {{SubstanceInteraction|MDAI + DMT|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Orion|[[Image:Positive.png]]|Vaporized hits of DMT seem harder to break through on, but the effect of the DMT seem prolonged. Strange visuals (small pinpoint kaleidoscope patters appear and dissappear), last for longer than the spice effects would last, by up to 25 minutes longer. Does not seem dangerous, but the fact it makes open eye visuals linger for so long is interesting...}} | ||
+ | }} | ||
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=== Cannabis === | === Cannabis === | ||
+ | |||
+ | Cannabis works as a potent anti-inflammatory and vasodilating medication. Those who use it often find that it goes well with almost every other drug, while those who seldom use it may find that when combined with psychedelic substances it can cause paranoia and uncomfortable potentiation. If you are unfamiliar with the ways cannabis synergizes with other substances, it is wise to start low and work your way up to a comfortable amount. Many find that oral cannabinoids act as a more potent vasodilator than smoked, making this a good option for countering the vasoconstriction of drugs like LSD and LSA. Many people also use cannabis to counter the nausea caused by other drugs. | ||
+ | |||
+ | |||
+ | ==== Cannabis + Harmalas (MAOI) ==== | ||
+ | {{SubstanceInteraction|Cannabis + Harmalas (MAOI)|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|House|[[Image:positive.png]]|Harmalas potentiate the effects of cannabis, adding a nice dreamy feel and tracers to the vision. Since they are both vasodilating compounds, some people experience headaches if combined in high doses. }} | ||
+ | }} | ||
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==== Piracetam + Psychedelics/Amphetamines ==== | ==== Piracetam + Psychedelics/Amphetamines ==== | ||
− | {{SubstanceInteraction|Piracetam + Psychedelics/Amphetamines|# | + | {{SubstanceInteraction|Piracetam + Psychedelics/Amphetamines|#805000|#E0A040|OK but|...| |
{{UserDescription|endlessness|[[Image:Positive.png]]|Trout notes that justin case, toad and others have reported substantial increase in potency of phenetylamines (such as MDMA, mescaline, amphetamines) and suggest dosage is halved. Possible potentiation of tryptamines too. There is very little data on the pharmacodynamics and toxicity of this mixture, so care is adviced, even though due to low toxicity of tryptamines and piracetam by itself, its possible the toxicity of mixture is also low.}} | {{UserDescription|endlessness|[[Image:Positive.png]]|Trout notes that justin case, toad and others have reported substantial increase in potency of phenetylamines (such as MDMA, mescaline, amphetamines) and suggest dosage is halved. Possible potentiation of tryptamines too. There is very little data on the pharmacodynamics and toxicity of this mixture, so care is adviced, even though due to low toxicity of tryptamines and piracetam by itself, its possible the toxicity of mixture is also low.}} | ||
+ | }} | ||
+ | |||
+ | ==== LSD + Piracetam ==== | ||
+ | |||
+ | {{SubstanceInteraction|LSD + Piracetam|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|I have been dosing piracetam daily for a few weeks now, and in that time I've done LSD twice. Definitely noticed that each time the piracetam VASTLY improves ability to articulate myself, ability to recall the trip and get into deeper meditative states. Piracetam also greatly helps my ability to write more clearly in my journals, improves my ability to play music and LSD enhances my musical creativity. All in all, very good combination.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Caffeine + Piracetam ==== | ||
+ | |||
+ | {{SubstanceInteraction|Caffeine + Piracetam|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Dream Weaver|[[Image:Positive.png]]|I occasionally dose piracetam anywhere from 800mg to 4 grams ingested on an empty stomach (dissolved in water). I find the synergy of caffeine + piracetam to be quite soothing. It is important not to ingest too much caffeine or an anxiety like feeling will occur/stomach problems... Mostly positive if done right. Effects are very soothing and uplifting. Make the most mundane task entertaining. You become quick and sharp as a whip. Effects are somewhat similar to 30mg xr adderall + 5-15mg valium (Note: Do not mix adderall and valium). Caffeine + Piracetam is a great combo! Ideal for mornings!}} | ||
}} | }} | ||
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=== DXM === | === DXM === | ||
+ | ==== DXM + Mushrooms ==== | ||
+ | |||
+ | {{SubstanceInteraction|DXM + Mushrooms|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Jabbawaya|[[Image:Positive.png]]|Great. Visually incredible. Cannabis at peak enhanced visuals even further. Use more mushrooms than DXM.}} | ||
+ | }} | ||
==== DXM + Cannabis ==== | ==== DXM + Cannabis ==== | ||
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− | ==== DXM + | + | ==== DXM + N2O ==== |
− | {{SubstanceInteraction|DXM + | + | {{SubstanceInteraction|DXM + N2O|#406040|#60FF60|OK|...| |
{{UserDescription|tigerstrike92|[[Image:Positive.png]]|Very, Very intense. Too much for some people, but for others, euphoria.}} | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|Very, Very intense. Too much for some people, but for others, euphoria.}} | ||
}} | }} | ||
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{{SubstanceInteraction|DXM + HBWR(LSA)|#805000|#E0A040|Depends|...| | {{SubstanceInteraction|DXM + HBWR(LSA)|#805000|#E0A040|Depends|...| | ||
{{UserDescription|tigerstrike92|[[Image:Positive.png]]|It really increases the psychedelia of dex, brings some awesomely colorful visions, but be very careful. Not much is known about the interactions of these two. I would not go above 3 HBWR seeds in combo.}} | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|It really increases the psychedelia of dex, brings some awesomely colorful visions, but be very careful. Not much is known about the interactions of these two. I would not go above 3 HBWR seeds in combo.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== DXM + DMT ==== | ||
+ | {{SubstanceInteraction|DXM + DMT|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|One of the most intense experiences I could possibly imagine. Classic Dissociative + DMT, but incomparable at the same time, I could say I like this combination better then DMT + Ketamine, or DMT + MXE, but its incomparable. It dissolves any preflight, or during anxiety whatsoever, the utterly intense godly power of DMT is given to YOU. }} | ||
}} | }} | ||
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{{SubstanceInteraction|Theobromine + LSD|#406040|#60FF60|OK|...| | {{SubstanceInteraction|Theobromine + LSD|#406040|#60FF60|OK|...| | ||
{{UserDescription|House|[[Image:Positive.png]]|OK. Noticeable synergy and potentiation}} | {{UserDescription|House|[[Image:Positive.png]]|OK. Noticeable synergy and potentiation}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|I haven't experimented too heavily with eating cacao on LSD, but I usually eat one or two handfulls of raw cacao nibs. I found the stimulation synergistic, very good for walking or running through the forest. I found that the cacao gets rid of the "shivers" I experience from LSD and warms me from the inside.}} | ||
}} | }} | ||
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}} | }} | ||
+ | |||
+ | ==== Theobromine + Bufotenine ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Bufotenine|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Entheogenerator|[[Image:Positive.png]]|I typically predose pure theobromine about 20-30 minutes before smoking bufotenine. Theobromine is a natural vasodilator and can be used to counteract the unpleasant physical effects of bufotenine caused by vasoconstriction. It may not eliminate the discomfort completely, but in my experience the theobromine powder has reduced the vasoconstriction to a more tolerable level. Raw cacao could probably be used to the same effect, but I have not tried. Ginger can be added to the mix to reduce nausea.}} | ||
+ | }} | ||
=== Kratom === | === Kratom === | ||
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− | === | + | === N2O === |
− | ==== | + | ==== N2O + Mescaline ==== |
− | {{SubstanceInteraction| | + | {{SubstanceInteraction|N2O + Mescaline|#406040|#60FF60|OK|...| |
+ | {{UserDescription|Jabbawaya|[[Image:Positive.png]]|N2O at peak of a mescaline trip was incredibly euphoric. Felt like psychedelic MDMA.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | |||
+ | ==== N2O + DMT ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|N2O + DMT|#406040|#60FF60|OK|...| | ||
{{UserDescription|endlessness|[[Image:Positive.png]]|When nitrous is inhaled immediately after dmt, its reported by some people to significantly enhance the experience.}} | {{UserDescription|endlessness|[[Image:Positive.png]]|When nitrous is inhaled immediately after dmt, its reported by some people to significantly enhance the experience.}} | ||
}} | }} | ||
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− | ==== | + | ==== N2O + LSD ==== |
− | {{SubstanceInteraction| | + | {{SubstanceInteraction|N2O + LSD|#406040|#60FF60|OK|...| |
{{UserDescription|ChaoticMethod|[[Image:Positive.png]]|OK. Very powerful. Be prepared to lie down and be somewhat paralyzed, depending on dosage.}} | {{UserDescription|ChaoticMethod|[[Image:Positive.png]]|OK. Very powerful. Be prepared to lie down and be somewhat paralyzed, depending on dosage.}} | ||
}} | }} | ||
− | ==== | + | ==== N2O + Ketamine ==== |
− | {{SubstanceInteraction| | + | {{SubstanceInteraction|N2O + Ketamine|#406040|#60FF60|OK|...| |
{{UserDescription|ChaoticMethod|[[Image:Positive.png]]|Amazing visuals. Out of body experience, very comfortable but no contact at all with the body.}} | {{UserDescription|ChaoticMethod|[[Image:Positive.png]]|Amazing visuals. Out of body experience, very comfortable but no contact at all with the body.}} | ||
}} | }} | ||
− | ==== | + | ==== N2O + Mushrooms ==== |
− | {{SubstanceInteraction| | + | {{SubstanceInteraction|N2O + Mushrooms|#406040|#60FF60|OK|...| |
− | {{UserDescription|Dante|[[Image:Positive.png]]|Amazing! For few minutes you are in a DMT like world. (I'd love to try LSD + | + | {{UserDescription|Dante|[[Image:Positive.png]]|Amazing! For few minutes you are in a DMT like world. (I'd love to try LSD + N2O)}} |
}} | }} | ||
− | |||
=== Alcohol (Ethanol) === | === Alcohol (Ethanol) === | ||
Line 779: | Line 915: | ||
{{UserDescription|obliguhl|[[Image:negative.png]]|Not so good. Caffeine disturbs the mushroom flow.}} | {{UserDescription|obliguhl|[[Image:negative.png]]|Not so good. Caffeine disturbs the mushroom flow.}} | ||
}} | }} | ||
+ | |||
+ | |||
+ | ==== LSD + Caffeine ==== | ||
+ | |||
+ | {{SubstanceInteraction|LSD + Caffeine|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|House|[[Image:Positive.png]]|I love coffee or yerba mate with LSD. Wonderful combo.}} | ||
+ | {{UserDescription|Shadowman-x|[[Image:Positive.png]]|I'm a bit of a coffee / mate junkie, so I find the combination quite synergistic. Smoking a spliff and drinking coffee on LSD makes me feel like all is right in the world and I can sit in meditation and take a good 30 minutes to drink my coffee and have my smoke. It lends itself to visual enhancement and incredible tingling sensations in the body, which for some people could make them quite restless, but I enjoy meditation on stimulants.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | === Melatonin === | ||
+ | |||
+ | |||
+ | |||
+ | ==== Melatonin + Mushrooms + Harmala + Cannabis + Changa ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Melatonin + Mushrooms + Harmala + Cannabis + Changa|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|Universecannon|[[Image:Positive.png]]|50-100mg melatonin (very meditative and harmala-esque for me. Combines well with others like a mind lube. A few hours later - lower dose of oral harmalas (preferably caapi) + mushrooms + smoked Cannabis + changa to top it off and push it all through. Amazing synergy. Need to balance the ratios accordingly though. You can leave out the melatonin if your not used to higher doses (they're not really that sleepy like the lower doses though, oddly). I prefer this combo after a day or to without sleep. Sleep deprivation is a powerful means of accessing altered states that's been used for thousands of years, like in the epic of Gilgamesh, for example. That's not for everyone though and works best with a raw, plant based diet.)}} | ||
+ | }} | ||
+ | |||
Latest revision as of 21:14, 19 November 2023
WARNING: | THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET! |
Contents
- 1 Introduction
- 2 Warning!
- 3 Psychedelics
- 3.1 DMT
- 3.2 Harmalas (MAOI)
- 3.2.1 Harmalas (MAOI) + Caffeine
- 3.2.2 Oral Harmalas (MAOI) + 5-MeO-DMT
- 3.2.3 Harmalas (MAOI) + Kava kava
- 3.2.4 Oral Harmalas (MAOI) + Opioids
- 3.2.5 Oral Harmalas (MAOI) + L-dopa
- 3.2.6 Oral Harmalas (MAOI) + tyrosine
- 3.2.7 Harmalas (MAOI) + Dissociatives
- 3.2.8 Harmalas (MAOI) + Corticosteroids / Prednisone
- 3.3 Mushrooms (psilocybin)
- 3.4 LSD
- 3.4.1 LSD + DMT
- 3.4.2 LSD + Ayahuasca + DMT
- 3.4.3 LSD + Mushrooms
- 3.4.4 LSD + MDMA
- 3.4.5 LSD + MDAI
- 3.4.6 LSD + Mescaline
- 3.4.7 LSD + Cannabis
- 3.4.8 LSD + Cannabis + Tobacco
- 3.4.9 LSD + MXE
- 3.4.10 LSD + Amphetamines
- 3.4.11 LSD + Harmalas (MAOI)
- 3.4.12 LSD + Amanita Muscaria/Pantherina
- 3.4.13 LSD + Alcohol
- 3.4.14 LSD + GHB
- 3.5 Mescaline
- 3.6 Iboga
- 3.7 MDMA
- 3.8 Ketamine
- 3.9 Salvia Divinorum
- 4 RC's
- 5 Medicine
- 6 Other
- 7 Links
Introduction
This article is about the interactions and effects of mixing different entheogens, both with each other and with medicine. Some combinations have a good synergy while others can be a DEADLY combination! Taking any substance carries a high responsibility, please read the WARNING section with great care!
Warning!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
Even though the interactions of certain substances are described here, it is extremely important to be safe at all times! This article is only to give information about interactions and their effects, this article is NOT meant for advice on taking any combination!
Many interactions described here are subjective descriptions, so what is shown here is only an indication on how certain combinations can affect you and how safe they are. Many times those effects are dependent on dose (of each substance), route of administration, timeline of administration, set and setting, your mood, your physical health, your mental health and many other factors.
Psychedelics
DMT
Some report dysphoria at lower doses. I (House) do not find this to be the case I find low doses incredibly euphoric. Higher doses can be known to go beyond human emotions and concepts. Higher doses of DMT are also known to cause strange bodily hallucinations like the feeling that you have stopped breathing, or that your heart has stopped beating. These hallucinations are common and can be countered with conscious relaxation and meditation prior and during the experience. You do not have to submit, per se, but beware that you may have to let go of certain intensities during the experience. It can easily be the most "intense" experience of your life for some people, and this is *NOT* a bad thing!
DMT + Alcohol
DMT + Alcohol | ||||||||||||||
Combination: |
SAFE But... |
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Generic information: |
... |
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User descriptions: |
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DMT + Benzodiazepines (Xanax)
DMT + Cannabis
DMT + Cannabis | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Dissociatives
DMT + Dissociatves | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DMT + Harmalas (MAOI)
DMT + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
Harmalas potentiate and prolong the effects of DMT, while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a MAOI is mandatory. |
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User descriptions: |
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DMT + LSD
DMT + LSD | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + MDMA
DMT + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DMT + Mescaline
DMT + Mescaline | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Mushrooms (psilocybin)
DMT + Mushrooms (psilocybin) | ||||||||||||||
Combination: |
OK |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Suboxone (Buprenorphine + Naloxone)
DMT + Suboxone | |||||
Combination: |
OK |
||||
Generic information: |
.... |
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User descriptions: |
|
Harmalas (MAOI)
Side effects include contraindication with certain substances. Make sure you understand interactions with substances before using them! At higher doses users experience nausea and vomiting, but this also isn't necessarily a bad thing, since harmalas are anti-parasitic, purging is often considered cleansing to both the body and the mind. Chest pressure is also common with ayahuasca. Feelings of having something heavy sitting on you. This is normal and if experienced just relax and let it be, it's part of the serpents coil.
Harmalas (MAOI) + Caffeine
Harmalas + caffeine | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Oral Harmalas (MAOI) + 5-MeO-DMT
Harmalas + 5-MeO-DMT | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Harmalas (MAOI) + Kava kava
Harmalas + Kava Kava | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
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User descriptions: |
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Oral Harmalas (MAOI) + Opioids
Oral Harmalas (MAOI) + Opioids | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure). |
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User descriptions: |
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Oral Harmalas (MAOI) + L-dopa
Harmalas + L-dopa | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Oral Harmalas (MAOI) + tyrosine
Harmalas + tyrosine | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Harmalas (MAOI) + Dissociatives
Harmalas (MAOI) + Dissociatives | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Even though there are reports on the net of people combining MXE with harmalas, in the right dosages harmalas + dissociatives have the potential to cause cardiac arrest. |
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User descriptions: |
Harmalas (MAOI) + Corticosteroids / Prednisone
Oral Harmalas (MAOI) + Corticosteroids / Prednisone | ||
Combination: |
BAD IDEA! |
|
Generic information: |
If you have been on prednisone for more than a couple of weeks you should NEVER stop the treatment abruptly; the dose should always be tapered down to allow your adrenal gland to 'wake up' and start producing glucocorticoids again. Harmala alkaloids inhibit CYP3a4 which has a role in metabolising prednisone, so the combination can magnify the effects of the steroid including adverse effects on glucose tolerance and lipid profiles.). |
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User descriptions: |
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Mushrooms (psilocybin)
I (House) think the most common side effect I hear about with shrooms is stomach discomfort. A lot of people don't know that you really are not supposed to consume any kind of raw mushroom. It's a rare case in the culinary and medicinal fields where raw mushrooms are told to be ingested. (I can think of a few exceptions, of course.) So for some ingesting the raw material can be very nauseating, myself included. Making a tea or the lemon tek is the way to go. By soaking raw mushrooms in lime juice, the citric acid literally cooks the mushrooms breaking down the cell walls. This is also known as a ceviche in the cooking world. Personally I just slip the shot of lime juice with the mushrooms in it back, it tastes good and I don't experience nausea this way. Some people filter out the mushroom material from the solution. Experiment. Taking too many mushrooms can lead to a feeling of being poisoned, but as far as I know no one has ever died from taking them on their own. Dose accordingly!
Mushrooms + Cannabis
Mushrooms + Cannabis | |||||
Combination: |
Depends |
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Generic information: |
... |
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User descriptions: |
|
Mushrooms + MDMA
Mushrooms + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + Harmalas (MAOI)
Mushrooms + Harmala (MAOI) | |||||||||||
Combination: |
SAFE But |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + Alcohol
Mushrooms + Alcohol | |||||||||||
Combination: |
SAFE But |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + Alcohol + Cocaine + MDMA
Mushrooms + Alcohol + Cocaine + MDMA | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + Cocaine
Mushrooms + Cocaine | |||||
Combination: |
SAFE But |
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Generic information: |
... |
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User descriptions: |
|
LSD
LSD is a potent vasoconstricting substance. This means it causes an increase in blood pressure by tightening the blood vessels in the body. This can be countered with vasodilating substances. Some find that oral hash completely diminishes the vasoconstriction. I like using transdermal magnesium prior to a dose to also help with things like jaw tension. Also, conscious relaxation, deep breaths, and massage (even done by the self) can help curb tension experienced from the drug. If you feel over stimulated or uncomfortable, you probably need to "Flow", so to speak. Get up, stretch, dance around, laugh, have an orgasm, be creative, play a musical instrument, take a hot shower. Things like this help with getting energy flowing and making meditation easier. Eat a bit of fruit on the come-up if you feel some unease! Many people find cannabis greatly eases the transition, but of course not everybody.
LSD + DMT
LSD + DMT | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
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User descriptions: |
|
LSD + Ayahuasca + DMT
LSD + Ayahuasca +DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mushrooms
LSD + Mushrooms | |||||||||||||||||
Combination: |
Depends |
||||||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + MDMA
LSD + MDMA | |||||||||||||||||
Combination: |
OK |
||||||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + MDAI
LSD + MDAI | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mescaline
LSD + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Cannabis
LSD + Cannabis | |||||||||||||||||
Combination: |
Depends |
||||||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + Cannabis + Tobacco
LSD + Cannabis + Tobacco | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + MXE
LSD + MXE | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + Amphetamines
LSD + Amphetamines | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
LSD + Harmalas (MAOI)
LSD + Harmalas (MAOI) | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + Amanita Muscaria/Pantherina
LSD + Amanita Muscaria/Pantherina | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Alcohol
LSD + Mescaline | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + GHB
LSD + GHB | |||||
Combination: |
Depends |
||||
Generic information: |
... |
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User descriptions: |
|
Mescaline
Mescaline is a phenethylamine that does not have an amphetamine group on the molecule, unlike MDMA. This allows it to be able to be used with harmalas without contraindication. A very gentle and long lasting psychedelic with great empathic and stimulating properties.
Mescaline + Caffeine
Mescaline + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Cannabis
Mescaline + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Harmalas (MAOI)
Mescaline + Harmala | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Alcohol
Mescaline + Alcohol | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Mescaline + MDMA
Mescaline + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga
Careful with this one! Much research and tests must be done before ingesting this substance. It is clinically proven to slow down a rhythm of the heart beat and has killed people because of this. A heart panel and EKG are common tests preformed before ingesting this substance. Please beware of this and do a lot of research before even considering this very profound medicine! Side effects include disorientation, immobility, nausea, in high doses for very long periods of time. Some people still can't drive a car 1 week after a flood dose, for example.
Iboga + LSD
Iboga + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Mushrooms
Iboga + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Cannabis
Iboga + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Harmalas (MAOI)
Iboga + Harmala | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Coffee
Iboga + Coffee | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA
The most common side effects of MDMA are jaw tension, feeling burnt-out the next day, and it's minimal amount of neurotoxicity. A lot of people "pre load" with substances that are neuroprotectant before, during, and after the experience. Neuroprotectants include cannabis, nootropics, vitamin C, 5-HTP, and others. Jaw tension can be countered again with transdermal magnesium, conscious relaxation, meditation and massage. As for feeling burnt-out, try to only redose a small amount one time or not at all. Constantly redosing can cause more burnout srensations. Also dosing too high. You might want to touch, hug, kiss, and tell how much you love everything around you, too.
Taking MDMA with MAOI and certain prescription medications can lead to seratonin syndrome and even death so plesse be careful!
MDMA + Harmalas (MAOI)
MDMA + Harmalas (MAOI) | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
MDMA + Cannabis
MDMA + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
MDMA + LSD + Ketamine + Cannabis
MDMA + LSD + Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + DMT + Ketamine
MDMA + DMT + Ketamine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine
Ketamine + LSD
Ketamine + LSD | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
Ketamine + LSD + Cannabis
Ketamine + LSD + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + Harmalas (MAOI)
Ketamine + Harmala | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
Harmalas are contraindicated with dissociatives, this means you do not want to combine them. At high doses the cardiovascular system can shut down. |
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User descriptions: |
|
Ketamine + Cannabis
Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine + DMT
Ketamine + Cannabis | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
Ketamine + LSD + DMT
Ketamine + LSD + DMT | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + MDMA
Ketamine + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Trippy as fook. So fun , but dangerous at high quantities of MDMA and Ket due to their different natures being sedative and stimulant. But extra trippy more like a lucid dream than a trip in my opinion
Ketamine + Alcohol
Ketamine + Alcohol | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Alcohol makes ketamine stronger or more potent to the nervous system making it easier to enter the k hole. Its fun but definitely bad for the cardiovascular side of things.
Salvia Divinorum
Salvia + DMT
Salvia + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Changa + Cannabis
Salvia + Changa + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Cannabis
Salvia + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Salvia + DMT
Salvia + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
RC's
2C-B
2C-B + Ketamine
2C-B + Ketamine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
2C-B + MDMA
2C-B + MDMA | |||||
Combination: |
OK, but |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + 2CB + K + Cannabis
MDMA + 2CB + K + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Had this mix over the space of 12 hours at a music festival , after coming out of the k hole after forgetting i had ingested 2cb , had a hell ride in the medical tent for hours. Wouldnt recommend this mix.
2C-I
2C-I + Cannabis
2C-I + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MXE
MXE + Cannabis
MXE + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
5-MeO-DALT + MXE
5-MeO-DALT + MXE | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
25i-NBOMe
25i-NBOMe + Cannabis + DMT
25i-NBOMe + Cannabis + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
AM-2201
AM-2201 + MDMA
AM-2201 + MDMA | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDAI
MDAI + DMT
MDAI + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Medicine
SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
MDMA + SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
Cannabis
Cannabis works as a potent anti-inflammatory and vasodilating medication. Those who use it often find that it goes well with almost every other drug, while those who seldom use it may find that when combined with psychedelic substances it can cause paranoia and uncomfortable potentiation. If you are unfamiliar with the ways cannabis synergizes with other substances, it is wise to start low and work your way up to a comfortable amount. Many find that oral cannabinoids act as a more potent vasodilator than smoked, making this a good option for countering the vasoconstriction of drugs like LSD and LSA. Many people also use cannabis to counter the nausea caused by other drugs.
Cannabis + Harmalas (MAOI)
Cannabis + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Other
Nootropics/Piracetam/Aniracetam
Piracetam + Psychedelics/Amphetamines
Piracetam + Psychedelics/Amphetamines | |||||
Combination: |
OK but |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Piracetam
LSD + Piracetam | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Caffeine + Piracetam
Caffeine + Piracetam | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava
Kava Kava + DMT
Kava Kava + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + LSD
Kava Kava + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + Cannabis
Kava Kava + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM
DXM + Mushrooms
DXM + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + Cannabis
DXM + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + Tobacco
DXM + Tobacco | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + N2O
DXM + N2O | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + HBWR (LSA)
DXM + HBWR(LSA) | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + DMT
DXM + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Chocolate/Theobromine
Theobromine, a methylated xanthine found in chocolate and yerba mate, is a stimulant and psychedelic potentiator.
Low doses combined with psychedelics causes noticeable potentiation and empathy. High doses have the potential to cause nausea and over stimulation, so start low and work up to a comfortable dose!
Theobromine + Caffeine
Theobromine + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Caffeine + Mescaline
Theobromine + Caffeine + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Passionflower
Theobromine + Passion Flower | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Harmalas (MAOI)
Theobromine + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + LSD
Theobromine + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Theobromine + Mushrooms
Theobromine + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Bufotenine
Theobromine + Bufotenine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kratom
Kratom + MXE
Kratom + MXE | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O
N2O + Mescaline
N2O + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + DMT
N2O + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + LSD
N2O + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + Ketamine
N2O + Ketamine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + Mushrooms
N2O + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Alcohol (Ethanol)
DXM + Alcohol
DXM + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Alcohol
Salvia + Alcohol | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + Alcohol
MDMA + Alcohol | ||||||||
Combination: |
Safe but |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Bufotenine + Alcohol
Bufotenine + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Caffeine
Mushrooms + Caffeine
Mushrooms + Caffeine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Caffeine
LSD + Caffeine | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Melatonin
Melatonin + Mushrooms + Harmala + Cannabis + Changa
Melatonin + Mushrooms + Harmala + Cannabis + Changa | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Benzos/Barbituates
Benzodiazepines can be reduce an agitated rough/unpleasant trip but are generally not recommended if other non-invasive supportive care-taking can be done, because these substances will dull the consciousness and might prevent the tripper from learning from the hard experience and integrating it.
Chlorpromazine + Psychedelics
Chlorpromazine + Psychedelics | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|