Difference between revisions of "Known substance-interactions and their effects"
Line 507: | Line 507: | ||
=== Chocolate/Theobromine === | === Chocolate/Theobromine === | ||
+ | Theobromine, a methylated xanthine found in chocolate and yerba mate, is a stimulant and psychedelic potentiator. | ||
+ | |||
+ | Low doses combined with psychedelics causes noticeable potentiation and empathy. | ||
+ | High doses have the potential to cause nausea and over stimulation, so start low and work up to a comfortable dose! | ||
+ | |||
+ | |||
+ | ==== Theobromine + Caffeine ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Caffeine|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|Aka The Mocha. Nice warm fuzzy sociable synergy.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Theobromine + Caffeine + Mescaline ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Caffeine + Mescaline|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|OK. Definite potentiation and synergy.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Theobromine + Passionflower ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Passion Flower|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:neutral.png]]|OK, but don't use a lot of theobromine. I have had psychedelic effects with this combination, but also intense nausea and bronchial-constriction at higher doses.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Theobromine + Caffeine + Mescaline ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Harmala|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|OK but do not use a lot of theobromine or harmala. A little goes a long way! Same thing goes here if you have a little too much of either theobromine or harmala expect nausea and vomiting. At appropriate doses however the synergy is very nice. Theobromine potentiates the harmalas and any psychedelics you take as well.}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | |||
+ | ==== Theobromine + LSD ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + LSD|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|OK. Noticeable synergy and potentiation}} | ||
+ | }} | ||
+ | |||
+ | |||
+ | ==== Theobromine + Mushrooms ==== | ||
+ | |||
+ | |||
+ | {{SubstanceInteraction|Theobromine + Mushrooms|#406040|#60FF60|OK|...| | ||
+ | {{UserDescription|tigerstrike92|[[Image:Positive.png]]|OK. Noticeable synergy and potentiation}} | ||
+ | }} | ||
Revision as of 01:19, 2 March 2012
WARNING: | THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET! |
Contents
- 1 Introduction
- 2 Warning!
- 3 Psychedelics
- 4 RC's
- 5 Medicine
- 6 Other
- 7 Links
Introduction
This article is about the interactions and effects of mixing different entheogens, both with each other and with medicine. Some combinations have a good synergy while others can be a DEADLY combination! Taking any substance carries a high responsibility, please read the WARNING section with great care!
Warning!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
Even though the interactions of certain substances are described here, it is extremely important to be safe at all times! This article is only to give information about interactions and their effects, this article is NOT meant for advice on taking any combination!
Many interactions described here are subjective descriptions, so what is shown here is only an indication on how certain combinations can affect you and how safe they are. Many times those effects are dependent on dose (of each substance), route of administration, timeline of administration, set and setting, your mood, your physical health, your mental health and many other factors.
Psychedelics
DMT
Some report dysphoria at lower doses. I (House) do not find this to be the case I find low doses incredibly euphoric. Higher doses can be known to go beyond human emotions and concepts. Higher doses of DMT are also known to cause strange bodily hallucinations like the feeling that you have stopped breathing, or that your heart has stopped beating. These hallucinations are common and can be countered with conscious relaxation and meditation prior and during the experience. You do not have to submit, per se, but beware that you may have to let go of certain intensities during the experience. It can easily be the most "intense" experience of your life for some people, and this is *NOT* a bad thing!
DMT + Harmalas (MAOI)
DMT + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
Harmalas potentiate and prolong the effects of DMT, while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a MAOI is mandatory. |
||||
User descriptions: |
|
DMT + Mushrooms (psilocybin)
DMT + Mushrooms (psilocybin) | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
DMT + LSD
DMT + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
DMT + MDMA
DMT + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DMT + Mescaline
DMT + Mescaline | ||||||||
Combination: |
OK But... |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
DMT + Alcohol
DMT + Alcohol | ||||||||
Combination: |
SAFE But... |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
DMT + Cannabis
DMT + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Harmalas (MAOI)
Side effects include contraindication with certain substances. Make sure you understand interactions with substances before using them! At higher doses users experience nausea and vomiting, but this also isn't necessarily a bad thing, since harmalas are anti-parasitic, purging is often considered cleansing to both the body and the mind. Chest pressure is also common with ayahuasca. Feelings of having something heavy sitting on you. This is normal and if experienced just relax and let it be, it's part of the serpents coil.
Harmalas (MAOI) + Caffeine
Harmalas (MAOI) + Kava kava
Harmalas + Kava Kava | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
Oral Harmalas (MAOI) + Opioids
Oral Harmalas (MAOI) + Opioids | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure). |
|
User descriptions: |
|
Harmalas (MAOI) + Dissociatives
Harmalas (MAOI) + Dissociatives | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Even though there are reports on the net of people combining MXE with harmalas, in the right dosages harmalas + dissociatives have the potential to stop the heart. |
|
User descriptions: |
|
Mushrooms (psilocybin)
I (House) think the most common side effect I hear about with shrooms is stomach discomfort. A lot of people don't know that you really are not supposed to consume any kind of raw mushroom. It's a rare case in the culinary and medicinal fields where raw mushrooms are told to be ingested. (I can think of a few exceptions, of course.) So for some ingesting the raw material can be very nauseating, myself included. Making a tea or the lemon tek is the way to go. By soaking raw mushrooms in lime juice, the citric acid literally cooks the mushrooms breaking down the cell walls. This is also known as a ceviche in the cooking world. Personally I just slip the shot of lime juice with the mushrooms in it back, it tastes good and I don't experience nausea this way. Some people filter out the mushroom material from the solution. Experiment. Taking too many mushrooms can lead to a feeling of being poisoned, but as far as I know no one has ever died from taking them on their own. Dose accordingly!
Mushrooms + Cannabis
Mushrooms + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + MDMA
Mushrooms + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + Harmalas (MAOI)
Mushrooms + Harmala (MAOI) | |||||
Combination: |
SAFE But |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + Alcohol
Mushrooms + Alcohol | |||||
Combination: |
SAFE But |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + Cocaine
Mushrooms + Cocaine | |||||
Combination: |
SAFE But |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD
LSD is a potent vasoconstricting substance. This means it causes an increase in blood pressure by tightening the blood vessels in the body. This can be countered with vasodilating substances. Some find that oral hash completely diminishes the vasoconstriction. I like using transdermal magnesium prior to a dose to also help with things like jaw tension. Also, conscious relaxation, deep breaths, and massage (even done by the self) can help curb tension experienced from the drug. If you feel over stimulated or uncomfortable, you probably need to "Flow", so to speak. Get up, stretch, dance around, laugh, have an orgasm, be creative, play a musical instrument, take a hot shower. Things like this help with getting energy flowing and making meditation easier. Eat a bit of fruit on the come-up if you feel some unease! Many people find cannabis greatly eases the transition, but of course not everybody.
LSD + DMT
LSD + DMT | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
LSD + Ayahuasca + DMT
LSD + Ayahuasca +DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mushrooms
LSD + Mushrooms | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + MDMA
LSD + MDMA | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
LSD + MDAI
LSD + MDAI | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mescaline
LSD + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Cannabis
LSD + Cannabis | |||||||||||
Combination: |
Depends |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
LSD + MXE
LSD + MXE | |||||||||||
Combination: |
Depends |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
LSD + Harmalas (MAOI)
LSD + Harmalas (MAOI) | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Mescaline
Mescaline is a phenethylamine that does not have an amphetamine group on the molecule, unlike MDMA. This allows it to be able to be used with harmalas without contraindication. I (House) would describe it as ancient, wise, stimulating, dreamy, empathic, psychedelic, and long lasting. If there was a divine, this would be it. It is very forgiving in high doses unlike some of the other psychedelics in the kingdom. It is found as an insecticide in the cacti family, and has been shown to be produced in higher amounts by stressed species.
Mescaline + Caffeine
Mescaline + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Cannabis
Mescaline + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Harmalas (MAOI)
Mescaline + Harmala | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga
Careful with this one! Much research and tests must be done before ingesting this substance. It is clinically proven to slow down a rhythm of the heart beat and has killed people because of this. A heart panel and EKG are common tests preformed before ingesting this substance. Please beware of this and do a lot of research before even considering this very profound medicine! Side effects include disorientation, immobility, nausea, in high doses for very long periods of time. Some people still can't drive a car 1 week after a flood dose, for example.
Iboga + LSD
Iboga + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Mushrooms
Iboga + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Cannabis
Iboga + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Harmalas (MAOI)
Iboga + Harmala | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Coffee
Iboga + Coffee | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA
The most common side effects of MDMA are jaw tension, feeling burnt-out the next day, and it's minimal amount of neurotoxicity. A lot of people "pre load" with substances that are neuroprotectant before, during, and after the experience. Neuroprotectants include cannabis, nootropics, vitamin C, 5-HTP, and others. Jaw tension can be countered again with transdermal magnesium, conscious relaxation, meditation and massage. As for feeling burnt-out, try to only redose a small amount one time or not at all. Constantly redosing can cause more burnout srensations. Also dosing too high. You might want to touch, hug, kiss, and tell how much you love everything around you, too.
Taking MDMA with MAOI and certain prescription medications can lead to seratonin syndrome and even death so plesse be careful!
MDMA + Harmalas (MAOI)
MDMA + Harmalas (MAOI) | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
MDMA + Cannabis
MDMA + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + LSD + Ketamine + Cannabis
MDMA + LSD + Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine
Ketamine + LSD
Ketamine + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + LSD + Cannabis
Ketamine + LSD + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + Harmalas (MAOI)
Ketamine + Harmala | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
Harmalas are contraindicated with dissociatives, this means you do not want to combine them. At high doses the cardiovascular system can shut down. |
||||
User descriptions: |
|
Ketamine + Cannabis
Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine + DMT
Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine + LSD + DMT
Ketamine + LSD + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia Divinorum
Salvia + DMT
Salvia + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Changa + Cannabis
Salvia + Changa + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Cannabis
Salvia + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
RC's
2C-B
2C-B + Ketamine
2C-B + Ketamine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + 2CB + K + Cannabis
MDMA + 2CB + K + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
2C-I
2C-I + Cannabis
2C-I + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDAI
MXE
MXE + Cannabis
MXE + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
5-MeO-DALT + MXE
5-MeO-DALT + MXE | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Medicine
SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE
Harmalas + Kava Kava | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
Other
Kava Kava
Kava Kava + DMT
Kava Kava + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + LSD
Kava Kava + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + Cannabis
Kava Kava + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM
DXM + Cannabis
DXM + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + Tobacco
DXM + Tobacco | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + NO2
DXM + NO2 | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + HBWR (LSA)
DXM + HBWR(LSA) | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Chocolate/Theobromine
Theobromine, a methylated xanthine found in chocolate and yerba mate, is a stimulant and psychedelic potentiator.
Low doses combined with psychedelics causes noticeable potentiation and empathy. High doses have the potential to cause nausea and over stimulation, so start low and work up to a comfortable dose!
Theobromine + Caffeine
Theobromine + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Caffeine + Mescaline
Theobromine + Caffeine + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Passionflower
Theobromine + Passion Flower | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Caffeine + Mescaline
Theobromine + Harmala | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + LSD
Theobromine + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Mushrooms
Theobromine + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kratom
NO2
Cannabis
Alcohol (Ethanol)
DXM + Alcohol
DXM + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Alcohol
Salvia + Alcohol | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + Alcohol
MDMA + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Caffeine
Mushrooms + Caffeine
Mushrooms + Caffeine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|