Difference between revisions of "Vasicine, Vasicinone and Deoxyvasicin"
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* XLogP3: 0.4 ([http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=442935&loc=ec_rcs pubchem]) | * XLogP3: 0.4 ([http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=442935&loc=ec_rcs pubchem]) | ||
* Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | * Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | ||
| − | * Solubility: Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus. | + | * Solubility: Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus.me/Harmalas_Extraction_and_Separation_Guide harmala extraction guide for more info]) |
=== Vasicinone === | === Vasicinone === | ||
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* XLogP3: 0.4 ([http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=442935&loc=ec_rcs pubchem]) | * XLogP3: 0.4 ([http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=442935&loc=ec_rcs pubchem]) | ||
* Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | * Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | ||
| − | * Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicinone can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus. | + | * Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicinone can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus.me/Harmalas_Extraction_and_Separation_Guide harmala extraction guide for more info] |
=== Deoxyvasicine === | === Deoxyvasicine === | ||
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* XLogP3: 0.4 | * XLogP3: 0.4 | ||
* Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | * Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: [http://www.chemicalland21.com/specialtychem/nd/VASICINE.htm 1], [http://indianmedicine.eldoc.ub.rug.nl/root/A/2091/ 2] | ||
| − | * Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus. | + | * Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check [http://wiki.dmt-nexus.me/Harmalas_Extraction_and_Separation_Guide harmala extraction guide for more info]) |
== Effects == | == Effects == | ||
Latest revision as of 20:57, 31 January 2012
Contents
- 1 Brief overview - What are Vasicine, Vasicinone and Deoxyvasicin?
- 2 Chemical and physical properties
- 3 Effects
- 4 Pharmacology, toxicity and general safety
- 5 Plants containing vasicine, vasicinone and deoxyvasicine
- 6 Extraction teks
- 7 Dosages and consumption methods
- 8 History of usage
- 9 Analysis of vasicine, vasicinone and deoxyvasicine
- 10 Scientific publications
- 11 Other links of interest
Brief overview - What are Vasicine, Vasicinone and Deoxyvasicin?
Chemical and physical properties
Vasicine
(3R)-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol;Peganine
Freebase Vasicine
 |
- Composition: C11H12N2O
- Molecular Weight: 188.22578 g/mol
- Melting point: 209-211° C (Decomposes) (source)
- XLogP3: 0.4 (pubchem)
- Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
- Solubility: Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info)
Vasicinone
(R)-2,3-dihydro-3-hydroxypyrrolo(2,1-b)quinazolin-9(1H)-one
Freebase Vasicine
 |
- Appearance: White powder
- Composition: C11H10N2O2
- Molecular Weight: 202.2093 g/mol
- Melting point: 203°-204° C (source)
- XLogP3: 0.4 (pubchem)
- Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
- Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicinone can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info
Deoxyvasicine
1,2,3,9-Tetrahydropyrrolo(2,1-b)quinazoline; Deoxypeganin;
Freebase Deoxyvasicine
 |
- Appearance: White to yellow powder
- Composition: C11H12N2
- Molecular Weight: 172.22638 g/mol
- Melting point: 86-87° C (source)
- XLogP3: 0.4
- Pharmacology: Uterotonic, abortifacient, bronchodilatory activity, expectorant, respiratory stimulant activity, moderate hypotensive activity (sources: 1, 2
- Solubility: Water: 1600 mg/l. Soluble in NaCl-saturated water (harmalas precipitate as HCl salts in NaCl-saturated water, hence vasicine can be separated from harmalas in peganum harmala. Check harmala extraction guide for more info)
