Difference between revisions of "Known substance-interactions and their effects"

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==== MDMA + Harmalas (MAOI) ====
 
==== MDMA + Harmalas (MAOI) ====
  
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{{SubstanceInteraction|DMT + Harmalas (MAOI)|#604040|#FF6060|BAD IDEA!|Hypertension, Serotonin Syndrome. '''Death''' can result out of this combination!|
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{{SubstanceInteraction|MDMA + Harmalas (MAOI)|#604040|#FF6060|BAD IDEA!|Hypertension, Serotonin Syndrome. '''Death''' can result out of this combination!|
 
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=== Ketamine ===
 
=== Ketamine ===

Revision as of 20:08, 20 January 2012

Error.png WARNING: THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!


Introduction

This article is about the interactions and effects of mixing different entheogens, both with each other and with medicine. Some combinations have a good synergy while others can be a DEADLY combination! Taking any substance carries a high responsibility, please read the WARNING section with great care!

Warning!

THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!

Even though the interactions of certain substances are described here, it is extremely important to be safe at all times! This article is only to give information about interactions and their effects, this article is NOT meant for advice on taking any combination!

Many interactions described here are subjective descriptions, so what is shown here is only an indication on how certain combinations can affect you and how safe they are. Many times those effects are dependent on dose (of each substance), route of administration, timeline of administration, set and setting, your mood, your physical health, your mental health and many other factors.

Psychedelics

DMT

DMT + Harmalas (MAOI)

DMT + Harmalas (MAOI) Information.png

Combination:

OK

Generic information:

Harmalas potentiate and prolong the effects of DMT, while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a MAOI is mandatory.

User descriptions:

House

Positive.png

Oral activation. Potentiation. Slowed-down effect. The two go hand in hand creating a perfect synergy.


DMT + Mushrooms (psilocybin)

DMT + Mushrooms (psilocybin) Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

Another profound synergy that seems to unlock the potential of the mushroom. Either @ peak or after.

The Traveler

Positive.png

Euphoric


DMT + LSD

DMT + LSD Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

Profound synergy. Really adds another more controlled layer to the hyperspatial flow. Highly recommended @ the peak or after the peak.

The Traveler

Positive.png

Euphoric, less anxiety. NOTE: best to take the DMT on the trail of the LSD and not on the peak of the LSD.


DMT + MDMA

DMT + MDMA Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

Euphoric, not as deep of a trip, but there is zero anxiety present which can be useful and awesome in it's own right.


DMT + Mescaline

DMT + Mescaline Information.png

Combination:

OK But...

Generic information:

...

User descriptions:

House

Positive.png

Great synergy here. Potentiates the mescaline and smooths it out.

The Traveler

Neutral.png

The mescaline seems to 'dull' the DMT. So there was not as much effects from smoking the DMT on Mescaline as you would expect.


DMT + Alcohol

DMT + Alcohol Information.png

Combination:

SAFE But...

Generic information:

...

User descriptions:

House

Negative.png

I find that combining the spice with a carcinogenic neurotoxin like alcohol completely negates the experience and masks it with toxic nullification (Yes, I am quite biased)

The Traveler

Negative.png

The alcohol did have a negative impact on me. I tried to drink a few beers beforehand to mitigate the anxiety of the pharmahuasca but that only resulted in dulling down, confusion and nausea.


DMT + THC

DMT + THC Information.png

Combination:

OK

Generic information:

...

User descriptions:

House

Positive.png

OK, although some people don't like it. If you are a daily smoker it shouldn't be a problem, but if you get anxiety from using THC occasionally it may be wise not to mix it with DMT.


Harmalas (MAOI)

Mushrooms (psilocybin)

LSD

LSD + MXE

LSD + MXE Information.png

Combination:

Depends

Generic information:

...

User descriptions:

Aetherius Rimor

Negative.png

Did 30mg of MXE in the 2nd hour of 2 hits. That's the only time I've not been at home and unable to verbalize/coordinate movement. Luckily that's what designated drivers are for! Won't combine them again. Definitely stronger effects than same dose of each independent of each other.

The Traveler

Negative.png

The MXE potentiates the LSD effects with more visuals but it also significantly alters motor function to the point of immobility at high doses.

Pandora

Positive.png

Radical and profound potentiation/synergy. 12+ hour trip and much longer to sleep. I really love the synergy of LSD+MXE but I'm the kind of person who naturally chills during a trip, so being pancaked by effects is just an extra plus for me.


Mescaline

Iboga

THC

RC's

2C-B

MDAI

MXE

Medicine

SSRI/SSRE

Other

MDMA

MDMA + Harmalas (MAOI)

MDMA + Harmalas (MAOI) Information.png

Combination:

BAD IDEA!

Generic information:

Hypertension, Serotonin Syndrome. Death can result out of this combination!

User descriptions:


Ketamine

Kava Kava

Alcohol (Ethanol)

Caffeine

Links

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