Difference between revisions of "Known substance-interactions and their effects"
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{{UserDescription|The Traveler|[[Image:Negative.png]]|The alcohol did have a negative impact on me. I tried to drink a few beers beforehand to mitigate the anxiety of the [[pharmahuasca]] but that only resulted in dulling down, confusion and nausea.}} | {{UserDescription|The Traveler|[[Image:Negative.png]]|The alcohol did have a negative impact on me. I tried to drink a few beers beforehand to mitigate the anxiety of the [[pharmahuasca]] but that only resulted in dulling down, confusion and nausea.}} | ||
{{UserDescription|Dante|[[Image:Negative.png]]|The Spice doesn't like Alcohol, you'll either wont remember or get a bad vibe.}} | {{UserDescription|Dante|[[Image:Negative.png]]|The Spice doesn't like Alcohol, you'll either wont remember or get a bad vibe.}} | ||
+ | {{UserDescription|Physics131|[[Image:neutral.png]]|Depends on the dose. 1 Beer is ok and helps to reduce pre tripping fear. A bottle of wine before tripping is very uncomfortable and probably dangerous imo.}} | ||
}} | }} | ||
==== DMT + Benzodiazepines (Xanax) ==== | ==== DMT + Benzodiazepines (Xanax) ==== | ||
− | {{SubstanceInteraction|DMT + enzodiazepines|#406040|# | + | {{SubstanceInteraction|DMT + enzodiazepines|#406040|#FF6060|BAD IDEA!|....| |
− | {{UserDescription|stoopkidpzpz|[[Image: | + | {{UserDescription|stoopkidpzpz|[[Image:negative.png]]|I took 1 MG of Xanax, and felt relaxed in about an hour. |
Decided to smoke some enhanced leaf... I smoked A LOT... I re-dosed for about 2 straight hours, 100mg doses each time. | Decided to smoke some enhanced leaf... I smoked A LOT... I re-dosed for about 2 straight hours, 100mg doses each time. | ||
When I was finished I took another 1 MG of Xanax... | When I was finished I took another 1 MG of Xanax... | ||
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{{SubstanceInteraction|Harmalas (MAOI) + Dissociatives|#604040|#FF6060|BAD IDEA!|Even though there are reports on the net of people combining MXE with harmalas, in the right dosages harmalas + dissociatives have the potential to cause cardiac arrest.|}} | {{SubstanceInteraction|Harmalas (MAOI) + Dissociatives|#604040|#FF6060|BAD IDEA!|Even though there are reports on the net of people combining MXE with harmalas, in the right dosages harmalas + dissociatives have the potential to cause cardiac arrest.|}} | ||
+ | |||
+ | |||
+ | ==== Harmalas (MAOI) + Corticosteroids / Prednisone ==== | ||
+ | |||
+ | {{SubstanceInteraction|Oral Harmalas (MAOI) + Corticosteroids / Prednisone|#604040|#FF6060|BAD IDEA!|If you have been on prednisone for more than a couple of weeks you should NEVER stop the treatment abruptly; the dose should always be tapered down to allow your adrenal gland to 'wake up' and start producing glucocorticoids again. | ||
+ | |||
+ | Harmala alkaloids inhibit CYP3a4 which has a role in metabolising prednisone, so the combination can magnify the effects of the steroid including adverse effects on glucose tolerance and lipid profiles.).| | ||
+ | }} | ||
=== Mushrooms (psilocybin) === | === Mushrooms (psilocybin) === | ||
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{{UserDescription|House|[[Image:Positive.png]]|I personally love the harmala + mushrooms synergy, but some have noted that the harmalas potentiate the mushrooms very much and have had rough trips! If you want to experiment with this combo, start low and work your way up!}} | {{UserDescription|House|[[Image:Positive.png]]|I personally love the harmala + mushrooms synergy, but some have noted that the harmalas potentiate the mushrooms very much and have had rough trips! If you want to experiment with this combo, start low and work your way up!}} | ||
− | {{UserDescription|Mindlusion|[[Image: | + | {{UserDescription|Mindlusion|[[Image:Positive.png]]|I tried this combo at a fairly high dose, it GREATLY potentiated the effects.. And I absolutely loved it, quite more then the intensity I was looking for. The intensity gets tiresome on the tail-end when your exhausted and hoping to sleep. If you try this combo, its great, just be prepared to trip for a LONG time.}} |
+ | |||
+ | {{UserDescription|pitubo|[[Image:Positive.png]]|Very interesting modification of the mushroom experience. Be careful to use only half or even less of your regular dose of mushrooms when combining with harmalas. Potentiation two- or threefold is to be expected even on moderate doses (100-125mg) of harmalas. Especially stronger doses of harmalas will intensify and prolong the mushroom trip far beyond what it would otherwise do. What I personally appreciate very much from this combination is the extended afterglow that keeps me in a special mood after the mushroom's effect wears out. }} | ||
}} | }} | ||
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{{UserDescription|Dante|[[Image:neutral.png]]|I took the Mushrooms while coming down from the LSD and I didn't feel any effect whatsoever. (EDIT: You probably have to take lots of Shrooms to fight the tollerance)}} | {{UserDescription|Dante|[[Image:neutral.png]]|I took the Mushrooms while coming down from the LSD and I didn't feel any effect whatsoever. (EDIT: You probably have to take lots of Shrooms to fight the tollerance)}} | ||
{{UserDescription|Shadowman-x|[[Image:neutral.png]]|I haven't experimented enough with this combination to say for sure. Only very small doses, and they were kind of hazy.}} | {{UserDescription|Shadowman-x|[[Image:neutral.png]]|I haven't experimented enough with this combination to say for sure. Only very small doses, and they were kind of hazy.}} | ||
+ | {{UserDescription|Solar Garlic|[[Image:Positive.png]]|This is one of my favorite combinations for tantric dance. I take around a gram of mushrooms right at peak. Fantastic synergy.}} | ||
}} | }} | ||
− | |||
==== LSD + MDMA ==== | ==== LSD + MDMA ==== | ||
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{{UserDescription|Universecannon|[[Image:Positive.png]]|Definitely has led to a bunch of paranoia at times (I'm prone to that with weed alone though) but if combined carefully it can be totally worth it although i never do it anymore (no lsd). If a large amount is smoked at the peak-especially if i have a low tolerance- then it can really catapult the experience into a sort of out of body type thing with full blown 3-d immerse visions, IME}} | {{UserDescription|Universecannon|[[Image:Positive.png]]|Definitely has led to a bunch of paranoia at times (I'm prone to that with weed alone though) but if combined carefully it can be totally worth it although i never do it anymore (no lsd). If a large amount is smoked at the peak-especially if i have a low tolerance- then it can really catapult the experience into a sort of out of body type thing with full blown 3-d immerse visions, IME}} | ||
{{UserDescription|Dante|[[Image:neutral.png]]|It gives a bit of anxiety, although the effect of LSD is potentiated for a little while. Be aware, it's very hard to roll a spliff while tripping }} | {{UserDescription|Dante|[[Image:neutral.png]]|It gives a bit of anxiety, although the effect of LSD is potentiated for a little while. Be aware, it's very hard to roll a spliff while tripping }} | ||
+ | {{UserDescription|Poppyfire|[[Image:Positive.png]]|Cannabis mellows out some of the more intense surges of body energy during the come-up of the LSD trip, which on their own can be unnerving at high doses. The combination of cannabis and LSD has been a favourite of mine for years, as the cannabis induces a calm state of mind, plus I personally don't enjoy taking LSD completely sober. }} | ||
}} | }} | ||
− | |||
− | |||
==== LSD + Cannabis + Tobacco==== | ==== LSD + Cannabis + Tobacco==== | ||
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{{SubstanceInteraction|LSD + Amphetamines|#805000|#E0A040|Depends|...| | {{SubstanceInteraction|LSD + Amphetamines|#805000|#E0A040|Depends|...| | ||
{{UserDescription|ChaoticMethod|[[Image:neutral.png]]|Somewhat safe but...Makes the LSD less visual and a bit more difficult to handle mentally because of the stress caused by the stimulants. It can be an interesting mix if partying but I would try to avoid it if possible. At least try to get pharmaceutical grade stimulants and not dirty street pills.}} | {{UserDescription|ChaoticMethod|[[Image:neutral.png]]|Somewhat safe but...Makes the LSD less visual and a bit more difficult to handle mentally because of the stress caused by the stimulants. It can be an interesting mix if partying but I would try to avoid it if possible. At least try to get pharmaceutical grade stimulants and not dirty street pills.}} | ||
+ | {{UserDescription|doubletrouble|[[Image:Negative.png]]|Took 10mg dextroamphetamine on the comedown from the LSD once. got severe spasms and "lightning flashes" and zaps through my brain and whole body. It was extremely uncomfortable. LSD in itself is a pretty potent stimulant. Just stupid to mix with another}} | ||
}} | }} | ||
− | |||
==== LSD + Harmalas (MAOI) ==== | ==== LSD + Harmalas (MAOI) ==== | ||
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{{UserDescription|Dante|[[Image:Positive.png]]|Great and jolly, but it makes the trip a bit blurry and less powerful. Don't over do it, your liver wont appreciate it!.}} | {{UserDescription|Dante|[[Image:Positive.png]]|Great and jolly, but it makes the trip a bit blurry and less powerful. Don't over do it, your liver wont appreciate it!.}} | ||
{{UserDescription|Shadowman-x|[[Image:neutral.png]]|I don't enjoy alcohol in general, so I'm slightly bias. When I was younger (15-16) I would shotgun beers on LSD and that was quite nice, but any hard alcohol combined with LSD turns you into a flailing, falling idiot apologizing for making such a big mess.}} | {{UserDescription|Shadowman-x|[[Image:neutral.png]]|I don't enjoy alcohol in general, so I'm slightly bias. When I was younger (15-16) I would shotgun beers on LSD and that was quite nice, but any hard alcohol combined with LSD turns you into a flailing, falling idiot apologizing for making such a big mess.}} | ||
+ | {{UserDescription|doubletrouble|[[Image:Positive.png]]|Amazing combo for dancing and having pure fun. Makes the come-up a bit easier too. For deeper tripping, not so much though.}} | ||
}} | }} | ||
− | |||
− | |||
==== LSD + GHB==== | ==== LSD + GHB==== | ||
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{{UserDescription|Dante|[[Image:negative.png]]|Some people love it, I don't. I don't like small bumps of K, so when I take it, it always end up taking over all the rest.}} | {{UserDescription|Dante|[[Image:negative.png]]|Some people love it, I don't. I don't like small bumps of K, so when I take it, it always end up taking over all the rest.}} | ||
}} | }} | ||
− | + | ||
+ | Trippy as fook. So fun , but dangerous at high quantities of MDMA and Ket due to their different natures being sedative and stimulant. But extra trippy more like a lucid dream than a trip in my opinion | ||
==== Ketamine + Alcohol ==== | ==== Ketamine + Alcohol ==== | ||
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}} | }} | ||
+ | |||
+ | Alcohol makes ketamine stronger or more potent to the nervous system making it easier to enter the k hole. Its fun but definitely bad for the cardiovascular side of things. | ||
===Salvia Divinorum=== | ===Salvia Divinorum=== | ||
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}} | }} | ||
+ | |||
+ | ==== 2C-B + MDMA ==== | ||
+ | |||
+ | {{SubstanceInteraction|2C-B + MDMA|#406040|#60FF60|OK, but|...| | ||
+ | {{UserDescription|Mindlusion|[[Image:Positive.png]]|Shulgin's classic combo. 2C-B is best taken 1.5-2h after dosing the MDMA! It smooths out the comedown, and the MDMA potentiates the 2C-B and makes for a powerful and unique empathogenic and psychedelic experience. But keep the MDMA dose low! Let 2C-B really bring the magic, increasing the MDMA dose only makes for a worse comedown and possible toxic effects!}} | ||
+ | }} | ||
==== MDMA + 2CB + K + Cannabis ==== | ==== MDMA + 2CB + K + Cannabis ==== | ||
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}} | }} | ||
+ | Had this mix over the space of 12 hours at a music festival , after coming out of the k hole after forgetting i had ingested 2cb , had a hell ride in the medical tent for hours. Wouldnt recommend this mix. | ||
=== 2C-I === | === 2C-I === | ||
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==== AM-2201 + MDMA ==== | ==== AM-2201 + MDMA ==== | ||
− | {{SubstanceInteraction|AM-2201 + MDMA|# | + | {{SubstanceInteraction|AM-2201 + MDMA|#805000|#E0A040|Depends|...| |
− | {{UserDescription|Orion|[[Image: | + | {{UserDescription|Orion|[[Image:Negative.png]]|Can be VERY hallucinogenic, only smoke a little! Bizarre and realistic and gory hallucinations (man with half a leg bleeding allover the place!) are possible, voices become distorted and merged and speak impossible ridiculous things. The hallucination is short lived.}} |
}} | }} | ||
− | |||
=== MDAI === | === MDAI === |
Latest revision as of 21:14, 19 November 2023
WARNING: | THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET! |
Contents
- 1 Introduction
- 2 Warning!
- 3 Psychedelics
- 3.1 DMT
- 3.2 Harmalas (MAOI)
- 3.2.1 Harmalas (MAOI) + Caffeine
- 3.2.2 Oral Harmalas (MAOI) + 5-MeO-DMT
- 3.2.3 Harmalas (MAOI) + Kava kava
- 3.2.4 Oral Harmalas (MAOI) + Opioids
- 3.2.5 Oral Harmalas (MAOI) + L-dopa
- 3.2.6 Oral Harmalas (MAOI) + tyrosine
- 3.2.7 Harmalas (MAOI) + Dissociatives
- 3.2.8 Harmalas (MAOI) + Corticosteroids / Prednisone
- 3.3 Mushrooms (psilocybin)
- 3.4 LSD
- 3.4.1 LSD + DMT
- 3.4.2 LSD + Ayahuasca + DMT
- 3.4.3 LSD + Mushrooms
- 3.4.4 LSD + MDMA
- 3.4.5 LSD + MDAI
- 3.4.6 LSD + Mescaline
- 3.4.7 LSD + Cannabis
- 3.4.8 LSD + Cannabis + Tobacco
- 3.4.9 LSD + MXE
- 3.4.10 LSD + Amphetamines
- 3.4.11 LSD + Harmalas (MAOI)
- 3.4.12 LSD + Amanita Muscaria/Pantherina
- 3.4.13 LSD + Alcohol
- 3.4.14 LSD + GHB
- 3.5 Mescaline
- 3.6 Iboga
- 3.7 MDMA
- 3.8 Ketamine
- 3.9 Salvia Divinorum
- 4 RC's
- 5 Medicine
- 6 Other
- 7 Links
Introduction
This article is about the interactions and effects of mixing different entheogens, both with each other and with medicine. Some combinations have a good synergy while others can be a DEADLY combination! Taking any substance carries a high responsibility, please read the WARNING section with great care!
Warning!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
THIS THREAD IS STILL 'IN THE MAKING' AND CAN CONTAIN WRONG DATA! DO NOT USE THIS THREAD AS A DRUG-INTERACTION GUIDE YET!
Even though the interactions of certain substances are described here, it is extremely important to be safe at all times! This article is only to give information about interactions and their effects, this article is NOT meant for advice on taking any combination!
Many interactions described here are subjective descriptions, so what is shown here is only an indication on how certain combinations can affect you and how safe they are. Many times those effects are dependent on dose (of each substance), route of administration, timeline of administration, set and setting, your mood, your physical health, your mental health and many other factors.
Psychedelics
DMT
Some report dysphoria at lower doses. I (House) do not find this to be the case I find low doses incredibly euphoric. Higher doses can be known to go beyond human emotions and concepts. Higher doses of DMT are also known to cause strange bodily hallucinations like the feeling that you have stopped breathing, or that your heart has stopped beating. These hallucinations are common and can be countered with conscious relaxation and meditation prior and during the experience. You do not have to submit, per se, but beware that you may have to let go of certain intensities during the experience. It can easily be the most "intense" experience of your life for some people, and this is *NOT* a bad thing!
DMT + Alcohol
DMT + Alcohol | ||||||||||||||
Combination: |
SAFE But... |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Benzodiazepines (Xanax)
DMT + Cannabis
DMT + Cannabis | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Dissociatives
DMT + Dissociatves | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DMT + Harmalas (MAOI)
DMT + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
Harmalas potentiate and prolong the effects of DMT, while at the same time it adds a slight psychedelic effect of it's own. For DMT to be orally active, a MAOI is mandatory. |
||||
User descriptions: |
|
DMT + LSD
DMT + LSD | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + MDMA
DMT + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DMT + Mescaline
DMT + Mescaline | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
DMT + Mushrooms (psilocybin)
DMT + Mushrooms (psilocybin) | ||||||||||||||
Combination: |
OK |
|||||||||||||
Generic information: |
... |
|||||||||||||
User descriptions: |
|
DMT + Suboxone (Buprenorphine + Naloxone)
DMT + Suboxone | |||||
Combination: |
OK |
||||
Generic information: |
.... |
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User descriptions: |
|
Harmalas (MAOI)
Side effects include contraindication with certain substances. Make sure you understand interactions with substances before using them! At higher doses users experience nausea and vomiting, but this also isn't necessarily a bad thing, since harmalas are anti-parasitic, purging is often considered cleansing to both the body and the mind. Chest pressure is also common with ayahuasca. Feelings of having something heavy sitting on you. This is normal and if experienced just relax and let it be, it's part of the serpents coil.
Harmalas (MAOI) + Caffeine
Harmalas + caffeine | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Oral Harmalas (MAOI) + 5-MeO-DMT
Harmalas + 5-MeO-DMT | |||||||||||
Combination: |
OK But... |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Harmalas (MAOI) + Kava kava
Harmalas + Kava Kava | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
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User descriptions: |
|
Oral Harmalas (MAOI) + Opioids
Oral Harmalas (MAOI) + Opioids | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure). |
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User descriptions: |
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Oral Harmalas (MAOI) + L-dopa
Harmalas + L-dopa | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Oral Harmalas (MAOI) + tyrosine
Harmalas + tyrosine | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Harmalas (MAOI) + Dissociatives
Harmalas (MAOI) + Dissociatives | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Even though there are reports on the net of people combining MXE with harmalas, in the right dosages harmalas + dissociatives have the potential to cause cardiac arrest. |
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User descriptions: |
Harmalas (MAOI) + Corticosteroids / Prednisone
Oral Harmalas (MAOI) + Corticosteroids / Prednisone | ||
Combination: |
BAD IDEA! |
|
Generic information: |
If you have been on prednisone for more than a couple of weeks you should NEVER stop the treatment abruptly; the dose should always be tapered down to allow your adrenal gland to 'wake up' and start producing glucocorticoids again. Harmala alkaloids inhibit CYP3a4 which has a role in metabolising prednisone, so the combination can magnify the effects of the steroid including adverse effects on glucose tolerance and lipid profiles.). |
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User descriptions: |
|
Mushrooms (psilocybin)
I (House) think the most common side effect I hear about with shrooms is stomach discomfort. A lot of people don't know that you really are not supposed to consume any kind of raw mushroom. It's a rare case in the culinary and medicinal fields where raw mushrooms are told to be ingested. (I can think of a few exceptions, of course.) So for some ingesting the raw material can be very nauseating, myself included. Making a tea or the lemon tek is the way to go. By soaking raw mushrooms in lime juice, the citric acid literally cooks the mushrooms breaking down the cell walls. This is also known as a ceviche in the cooking world. Personally I just slip the shot of lime juice with the mushrooms in it back, it tastes good and I don't experience nausea this way. Some people filter out the mushroom material from the solution. Experiment. Taking too many mushrooms can lead to a feeling of being poisoned, but as far as I know no one has ever died from taking them on their own. Dose accordingly!
Mushrooms + Cannabis
Mushrooms + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + MDMA
Mushrooms + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mushrooms + Harmalas (MAOI)
Mushrooms + Harmala (MAOI) | |||||||||||
Combination: |
SAFE But |
||||||||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + Alcohol
Mushrooms + Alcohol | |||||||||||
Combination: |
SAFE But |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
Mushrooms + Alcohol + Cocaine + MDMA
Mushrooms + Alcohol + Cocaine + MDMA | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
... |
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User descriptions: |
|
Mushrooms + Cocaine
Mushrooms + Cocaine | |||||
Combination: |
SAFE But |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD
LSD is a potent vasoconstricting substance. This means it causes an increase in blood pressure by tightening the blood vessels in the body. This can be countered with vasodilating substances. Some find that oral hash completely diminishes the vasoconstriction. I like using transdermal magnesium prior to a dose to also help with things like jaw tension. Also, conscious relaxation, deep breaths, and massage (even done by the self) can help curb tension experienced from the drug. If you feel over stimulated or uncomfortable, you probably need to "Flow", so to speak. Get up, stretch, dance around, laugh, have an orgasm, be creative, play a musical instrument, take a hot shower. Things like this help with getting energy flowing and making meditation easier. Eat a bit of fruit on the come-up if you feel some unease! Many people find cannabis greatly eases the transition, but of course not everybody.
LSD + DMT
LSD + DMT | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
LSD + Ayahuasca + DMT
LSD + Ayahuasca +DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mushrooms
LSD + Mushrooms | |||||||||||||||||
Combination: |
Depends |
||||||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + MDMA
LSD + MDMA | |||||||||||||||||
Combination: |
OK |
||||||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + MDAI
LSD + MDAI | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Mescaline
LSD + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
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User descriptions: |
|
LSD + Cannabis
LSD + Cannabis | |||||||||||||||||
Combination: |
Depends |
||||||||||||||||
Generic information: |
... |
||||||||||||||||
User descriptions: |
|
LSD + Cannabis + Tobacco
LSD + Cannabis + Tobacco | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + MXE
LSD + MXE | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
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User descriptions: |
|
LSD + Amphetamines
LSD + Amphetamines | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
LSD + Harmalas (MAOI)
LSD + Harmalas (MAOI) | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
|||||||||||||
User descriptions: |
|
LSD + Amanita Muscaria/Pantherina
LSD + Amanita Muscaria/Pantherina | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Alcohol
LSD + Mescaline | ||||||||||||||
Combination: |
Depends |
|||||||||||||
Generic information: |
... |
|||||||||||||
User descriptions: |
|
LSD + GHB
LSD + GHB | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline
Mescaline is a phenethylamine that does not have an amphetamine group on the molecule, unlike MDMA. This allows it to be able to be used with harmalas without contraindication. A very gentle and long lasting psychedelic with great empathic and stimulating properties.
Mescaline + Caffeine
Mescaline + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Cannabis
Mescaline + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Harmalas (MAOI)
Mescaline + Harmala | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Mescaline + Alcohol
Mescaline + Alcohol | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Mescaline + MDMA
Mescaline + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga
Careful with this one! Much research and tests must be done before ingesting this substance. It is clinically proven to slow down a rhythm of the heart beat and has killed people because of this. A heart panel and EKG are common tests preformed before ingesting this substance. Please beware of this and do a lot of research before even considering this very profound medicine! Side effects include disorientation, immobility, nausea, in high doses for very long periods of time. Some people still can't drive a car 1 week after a flood dose, for example.
Iboga + LSD
Iboga + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Mushrooms
Iboga + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Iboga + Cannabis
Iboga + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Harmalas (MAOI)
Iboga + Harmala | ||||||||
Combination: |
Depends |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Iboga + Coffee
Iboga + Coffee | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA
The most common side effects of MDMA are jaw tension, feeling burnt-out the next day, and it's minimal amount of neurotoxicity. A lot of people "pre load" with substances that are neuroprotectant before, during, and after the experience. Neuroprotectants include cannabis, nootropics, vitamin C, 5-HTP, and others. Jaw tension can be countered again with transdermal magnesium, conscious relaxation, meditation and massage. As for feeling burnt-out, try to only redose a small amount one time or not at all. Constantly redosing can cause more burnout srensations. Also dosing too high. You might want to touch, hug, kiss, and tell how much you love everything around you, too.
Taking MDMA with MAOI and certain prescription medications can lead to seratonin syndrome and even death so plesse be careful!
MDMA + Harmalas (MAOI)
MDMA + Harmalas (MAOI) | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
MDMA + Cannabis
MDMA + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
MDMA + LSD + Ketamine + Cannabis
MDMA + LSD + Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + DMT + Ketamine
MDMA + DMT + Ketamine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine
Ketamine + LSD
Ketamine + LSD | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
Ketamine + LSD + Cannabis
Ketamine + LSD + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + Harmalas (MAOI)
Ketamine + Harmala | |||||
Combination: |
BAD IDEA! |
||||
Generic information: |
Harmalas are contraindicated with dissociatives, this means you do not want to combine them. At high doses the cardiovascular system can shut down. |
||||
User descriptions: |
|
Ketamine + Cannabis
Ketamine + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Ketamine + DMT
Ketamine + Cannabis | |||||||||||
Combination: |
OK |
||||||||||
Generic information: |
... |
||||||||||
User descriptions: |
|
Ketamine + LSD + DMT
Ketamine + LSD + DMT | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Ketamine + MDMA
Ketamine + MDMA | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Trippy as fook. So fun , but dangerous at high quantities of MDMA and Ket due to their different natures being sedative and stimulant. But extra trippy more like a lucid dream than a trip in my opinion
Ketamine + Alcohol
Ketamine + Alcohol | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Alcohol makes ketamine stronger or more potent to the nervous system making it easier to enter the k hole. Its fun but definitely bad for the cardiovascular side of things.
Salvia Divinorum
Salvia + DMT
Salvia + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Changa + Cannabis
Salvia + Changa + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Cannabis
Salvia + Cannabis | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Salvia + DMT
Salvia + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
RC's
2C-B
2C-B + Ketamine
2C-B + Ketamine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
2C-B + MDMA
2C-B + MDMA | |||||
Combination: |
OK, but |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + 2CB + K + Cannabis
MDMA + 2CB + K + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
Had this mix over the space of 12 hours at a music festival , after coming out of the k hole after forgetting i had ingested 2cb , had a hell ride in the medical tent for hours. Wouldnt recommend this mix.
2C-I
2C-I + Cannabis
2C-I + Cannabis | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MXE
MXE + Cannabis
MXE + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
5-MeO-DALT + MXE
5-MeO-DALT + MXE | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
25i-NBOMe
25i-NBOMe + Cannabis + DMT
25i-NBOMe + Cannabis + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
AM-2201
AM-2201 + MDMA
AM-2201 + MDMA | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDAI
MDAI + DMT
MDAI + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Medicine
SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
MDMA + SSRI/SSRE
Harmalas (MAOI) + SSRI/SSRE | ||
Combination: |
BAD IDEA! |
|
Generic information: |
Hypertension, Serotonin Syndrome. Death can result out of this combination! |
|
User descriptions: |
|
Cannabis
Cannabis works as a potent anti-inflammatory and vasodilating medication. Those who use it often find that it goes well with almost every other drug, while those who seldom use it may find that when combined with psychedelic substances it can cause paranoia and uncomfortable potentiation. If you are unfamiliar with the ways cannabis synergizes with other substances, it is wise to start low and work your way up to a comfortable amount. Many find that oral cannabinoids act as a more potent vasodilator than smoked, making this a good option for countering the vasoconstriction of drugs like LSD and LSA. Many people also use cannabis to counter the nausea caused by other drugs.
Cannabis + Harmalas (MAOI)
Cannabis + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Other
Nootropics/Piracetam/Aniracetam
Piracetam + Psychedelics/Amphetamines
Piracetam + Psychedelics/Amphetamines | |||||
Combination: |
OK but |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Piracetam
LSD + Piracetam | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Caffeine + Piracetam
Caffeine + Piracetam | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava
Kava Kava + DMT
Kava Kava + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + LSD
Kava Kava + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kava Kava + Cannabis
Kava Kava + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM
DXM + Mushrooms
DXM + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + Cannabis
DXM + Cannabis | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + Tobacco
DXM + Tobacco | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + N2O
DXM + N2O | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + HBWR (LSA)
DXM + HBWR(LSA) | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
DXM + DMT
DXM + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Chocolate/Theobromine
Theobromine, a methylated xanthine found in chocolate and yerba mate, is a stimulant and psychedelic potentiator.
Low doses combined with psychedelics causes noticeable potentiation and empathy. High doses have the potential to cause nausea and over stimulation, so start low and work up to a comfortable dose!
Theobromine + Caffeine
Theobromine + Caffeine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Caffeine + Mescaline
Theobromine + Caffeine + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Passionflower
Theobromine + Passion Flower | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Harmalas (MAOI)
Theobromine + Harmalas (MAOI) | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + LSD
Theobromine + LSD | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Theobromine + Mushrooms
Theobromine + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Theobromine + Bufotenine
Theobromine + Bufotenine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Kratom
Kratom + MXE
Kratom + MXE | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O
N2O + Mescaline
N2O + Mescaline | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + DMT
N2O + DMT | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + LSD
N2O + LSD | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + Ketamine
N2O + Ketamine | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
N2O + Mushrooms
N2O + Mushrooms | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Alcohol (Ethanol)
DXM + Alcohol
DXM + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Salvia + Alcohol
Salvia + Alcohol | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
MDMA + Alcohol
MDMA + Alcohol | ||||||||
Combination: |
Safe but |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Bufotenine + Alcohol
Bufotenine + Alcohol | |||||
Combination: |
Safe but |
||||
Generic information: |
... |
||||
User descriptions: |
|
Caffeine
Mushrooms + Caffeine
Mushrooms + Caffeine | |||||
Combination: |
Depends |
||||
Generic information: |
... |
||||
User descriptions: |
|
LSD + Caffeine
LSD + Caffeine | ||||||||
Combination: |
OK |
|||||||
Generic information: |
... |
|||||||
User descriptions: |
|
Melatonin
Melatonin + Mushrooms + Harmala + Cannabis + Changa
Melatonin + Mushrooms + Harmala + Cannabis + Changa | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|
Benzos/Barbituates
Benzodiazepines can be reduce an agitated rough/unpleasant trip but are generally not recommended if other non-invasive supportive care-taking can be done, because these substances will dull the consciousness and might prevent the tripper from learning from the hard experience and integrating it.
Chlorpromazine + Psychedelics
Chlorpromazine + Psychedelics | |||||
Combination: |
OK |
||||
Generic information: |
... |
||||
User descriptions: |
|