Phlux's Telepathine Tek - Revision history

TheTraveler: Text replace - "dmt-nexus.com" to "dmt-nexus.me"

2012-01-31T19:56:45Z

Text replace - "dmt-nexus.com" to "dmt-nexus.me"

TheTraveler: /* Isolation of Harmine */

2009-11-15T22:34:38Z

‎Isolation of Harmine

TheTraveler: /* Isolation of Harmine */

2009-11-15T22:21:11Z

‎Isolation of Harmine

TheTraveler at 22:11, 15 November 2009

2009-11-15T22:11:41Z

TheTraveler at 22:05, 15 November 2009

2009-11-15T22:05:27Z

Amor fati: transcribed

2009-11-14T00:23:23Z

transcribed

New page

{{ShowInfo|[[Image:Note_error.png]]|'''Note:'''|This page is a transcription of Phlux's Telepathine Tek<ref>Harmine and Harmaline Separation - My Photo Tek - Telepathine Tek[http://www.dmt-nexus.com/forum/default.aspx?g=posts&t=5749]</ref>. The content is to remain accurate as such.}}

Telepathine Teq
Isolating the Harmine and Harmaline from a Rue Extraction
a collaborative effort by Dynamix / Phlux- / Monad / Root

Disclaimer

The information presented herein is for ENTERTAINMENT PURPOSES ONLY and can be found in ethnobotanical literature. The substances listed in this document may be illegal to ingest and/or possess. The author assumes no responsibility should the information presented here be used, misused, misunderstood, inaccurate or even read. Reading this document constitutes an agreement to these terms. If you are afraid you might attempt to use the substances mentioned here in illegal ways, STOP READING NOW.

This document may be reproduced verbatim, in whole or in part, by any means, and distributed freely by whatever means available, provided no charge is made for the copy, this disclaimer is included and credit is given to the author.

Introduction

This is by no means my tek - i take no credit for the information contained within. After performing the manske extraction on rue one is left with a freebase mixture of Harmaline and Harmine and allthough this can be used as is having them separate is nice for more control.
To separate the two one can take advantage of the difference in their pKa values.
The pKa value of a substance is the pH at which half of the substance is in freebase form and the other half in salt form.
Harmine - pKa=7.7
Harmaline - pKa=9.8
According to Infundibulum(The Nexus) the best pH to precipitate harmine is at pH 8.75 because at this pH one will in theory get at around 92% harmine and 8% harmaline.
If the harmine is precipitated at pH 8 one would get a much purer harmine but not all the harmine in the solution will precipitate.
A calculator is available in the original post here

In this tek - Step 2-4 are just for a purer product - after step 1 the solution could be filtered and one could proceed directly to step 5.

Isolation of Harmine

The Manske Mixture (freebase form) 500mg is used here

Step 1 : Disolve the freebase in acidic water (acidify with a little bit of vinegar)

Step 2 : Filter the solution and increase the pH slowly to 8 using a sodium carbonate solution.

Within a few hours hours precipitates are visible and a few hours later...

Step 3 : When the xtals have formed completely the solution can be poured off

Then the xtals dried before collection

This yeilded 150mg of rather pure harmine

Step 5 : The solutions pH can now be pushed up to 8.75 using a sodium carbonate solution.

Within hours a loads more xtals precipitate

Which can be collected and dried
This yeilded 130mg fairly pure harmaline

Step 6 : Increase the pH to the max using sodium carbonate solution to precipitate the Harmaline.
The Harmaline was not as visually pleasing as it grew - it just looked like white sand.

220mg was dried and collected.

It is easy to pour the solution off the Harmine xtals but the Harmaline filtration was more tricky an easy kitchen solution that worked was a syringe with a peice of coffee filter paper cut and folded to size.
When all the solution has been filtered the syringe plunger can be used to press the remaining water out and remove the Harmaline as a soft tablet which can then be dried completely.

== Reference ==
<references/>

[[Category:Extraction Tek]]

@@ Line 1: / Line 1: @@
-{{ShowInfo|[[Image:Note_error.png]]|'''Note:'''|This page is a transcription of Phlux's Telepathine Tek<ref>Harmine and Harmaline Separation - My Photo Tek - Telepathine Tek[http://www.dmt-nexus.com/forum/default.aspx?g=posts&t=5749]</ref>. The content is to remain accurate as such.}}
+{{ShowInfo|[[Image:Note_error.png]]|'''Note:'''|This page is a transcription of Phlux's Telepathine Tek<ref>Harmine and Harmaline Separation - My Photo Tek - Telepathine Tek[http://www.dmt-nexus.me/forum/default.aspx?g=posts&t=5749]</ref>. The content is to remain accurate as such.}}
 Telepathine Teq
@@ Line 20: / Line 20: @@
 According to Infundibulum(The Nexus) the best pH to precipitate harmine is at pH 8.75 because at this pH one will in theory get at around 92% harmine and 8% harmaline.
 If the harmine is precipitated at pH 8 one would get a much purer harmine but not all the harmine in the solution will precipitate.
-A calculator is available in the original post [http://www.dmt-nexus.com/forum/default.aspx?g=posts&m=68410 here]
+A calculator is available in the original post [http://www.dmt-nexus.me/forum/default.aspx?g=posts&m=68410 here]
 In this tek - Step 2-4 are just for a purer product - after step 1 the solution could be filtered and one could proceed directly to step 5.

@@ Line 54: / Line 54: @@
 === Step 3 ===
-When the xtals have formed completely the solution can be poured off
+<table>
-Then the xtals dried before collection
+=== Step 4 ===
-This yeilded 150mg of rather pure harmine
+=== Step 5 ===
-Step 5 : The solutions pH can now be pushed up to 8.75 using a sodium carbonate solution.
+=== Step 6 ===
 Increase the pH to the max using sodium carbonate solution to precipitate the Harmaline.
-−
-−
-Within hours a loads more xtals precipitate
-−
-−
-−
-−
-−
-−
-Which can be collected and dried
-This yeilded 130mg fairly pure harmaline
-−
-−
-Step 6 : Increase the pH to the max using sodium carbonate solution to precipitate the Harmaline.
 The Harmaline was not as visually pleasing as it grew - it just looked like white sand.
+<table>
+<tr>
-mg was dried and collected.
+<td>[[Image:E1.jpg|thumb|left|500px|220mg was dried and collected.]]</td>
+</tr>
+</table>
+<table>
-It is easy to pour the solution off the Harmine xtals but the Harmaline filtration was more tricky an easy kitchen solution that worked was a syringe with a peice of coffee filter paper cut and folded to size.
+<tr>
-When all the solution has been filtered the syringe plunger can be used to press the remaining water out and remove the Harmaline as a soft tablet which can then be dried completely.
+<td>[[Image:G1.jpg|thumb|left|500px|It is easy to pour the solution off the Harmine xtals but the Harmaline filtration was more tricky an easy kitchen solution that worked was a syringe with a peice of coffee filter paper cut and folded to size.
 == Reference ==

@@ Line 25: / Line 25: @@
 == Isolation of Harmine==
+<table>
-The Manske Mixture (freebase form) 500mg is used here
+<tr>
 === Step 1 ===
-Disolve the freebase in acidic water (acidify with a little bit of vinegar)
+<table>
 === Step 2 ===
-Filter the solution and increase the pH slowly to 8 using a sodium carbonate solution.
+<table>
+<tr>
-Within a few hours hours precipitates are visible and a few hours later...
+<td>[[Image:Filter.JPG|thumb|left|500px|Filter the solution and increase the pH slowly to 8 using a sodium carbonate solution.]]</td>
 === Step 3 ===
@@ Line 70: / Line 87: @@
 It is easy to pour the solution off the Harmine xtals but the Harmaline filtration was more tricky an easy kitchen solution that worked was a syringe with a peice of coffee filter paper cut and folded to size.
 When all the solution has been filtered the syringe plunger can be used to press the remaining water out and remove the Harmaline as a soft tablet which can then be dried completely.
 == Reference ==

@@ Line 10: / Line 10: @@
 This document may be reproduced verbatim, in whole or in part, by any means, and distributed freely by whatever means available, provided no charge is made for the copy, this disclaimer is included and credit is given to the author.
 == Introduction ==
@@ Line 17: / Line 16: @@
 To separate the two one can take advantage of the difference in their pKa values.
 The pKa value of a substance is the pH at which half of the substance is in freebase form and the other half in salt form.
-Harmine - pKa=7.7
+* Harmine - pKa=7.7
-Harmaline - pKa=9.8
+* Harmaline - pKa=9.8
 According to Infundibulum(The Nexus) the best pH to precipitate harmine is at pH 8.75 because at this pH one will in theory get at around 92% harmine and 8% harmaline.
 If the harmine is precipitated at pH 8 one would get a much purer harmine but not all the harmine in the solution will precipitate.
-A calculator is available in the original post here
+A calculator is available in the original post [http://www.dmt-nexus.com/forum/default.aspx?g=posts&m=68410 here]
 In this tek - Step 2-4 are just for a purer product - after step 1 the solution could be filtered and one could proceed directly to step 5.
 == Isolation of Harmine==