Muscimol and ibotenic acid - Revision history

Robotussin: /* Plants containing Muscimol and Ibotenic Acid */

2012-04-07T00:04:33Z

‎Plants containing Muscimol and Ibotenic Acid

2012-04-07T00:02:14Z

‎Other links of interest

2012-04-07T00:01:02Z

‎Other links of interest

2012-04-07T00:00:28Z

‎Other links of interest

2012-04-06T23:59:47Z

‎Other links of interest

2012-04-06T23:57:23Z

‎Plants containing Muscimol and Ibotenic Acid

2012-04-06T23:56:49Z

‎Plants containing Muscimol and Ibotenic Acid

2012-04-06T23:54:24Z

‎Dosages and consumption methods

2012-04-06T23:35:51Z

‎Dosages and consumption methods

2012-04-06T23:21:26Z

‎Pharmacology, toxicity and general safety

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 == Plants containing Muscimol and Ibotenic Acid ==
-Muscimol is produced naturally in the mushrooms Amanita Muscaria[http://wiki.dmt-nexus.me/Amanita_muscaria], Amanita pantherina, and Amanita gemmata, along with muscarine, muscazone, and ibotenic acid. A. muscaria and A. pantherina should be eaten with caution and prepared properly to lessen effects of nausea.; no official deaths from poisoning have been recorded from A. muscaria and A. pantherina. In A. muscaria, the layer just below the skin of the cap contains the highest amount of muscimol, and is therefore the most psychoactive portion.
+Muscimol is produced naturally in the mushrooms Amanita Muscaria[http://www.erowid.org/plants/amanitas/amanitas.shtml], Amanita pantherina, and Amanita gemmata, along with muscarine, muscazone, and ibotenic acid. A. muscaria and A. pantherina should be eaten with caution and prepared properly to lessen effects of nausea.; no official deaths from poisoning have been recorded from A. muscaria and A. pantherina. In A. muscaria, the layer just below the skin of the cap contains the highest amount of muscimol, and is therefore the most psychoactive portion.
 == Extraction teks ==

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 == Other links of interest ==
-[Erowid Psychoactive Amanita Page[http://www.erowid.org/plants/amanitas/amanitas.shtml]]
+http://www.erowid.org/plants/amanitas/amanitas.shtml
 {{Page Footer|Allies and Associated Alkaloids}}
 [[Category:Alkaloids]]

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 == Other links of interest ==
-[Erowid Psychoactive Amanita Page][http://www.erowid.org/plants/amanitas/amanitas.shtml]
+[Erowid Psychoactive Amanita Page[http://www.erowid.org/plants/amanitas/amanitas.shtml]]
 {{Page Footer|Allies and Associated Alkaloids}}
 [[Category:Alkaloids]]

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 == Other links of interest ==
-[http://www.erowid.org/plants/amanitas/amanitas.shtml]
+[Erowid Psychoactive Amanita Page][http://www.erowid.org/plants/amanitas/amanitas.shtml]
 {{Page Footer|Allies and Associated Alkaloids}}
 [[Category:Alkaloids]]

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 == Other links of interest ==
+[http://www.erowid.org/plants/amanitas/amanitas.shtml]
 {{Page Footer|Allies and Associated Alkaloids}}
 [[Category:Alkaloids]]

← Older revision		Revision as of 23:54, 6 April 2012
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	It is suggested that a tea be made with the dried mushrooms to convert Ibotenic Acid into Muscimol. (Recipe Below)		It is suggested that a tea be made with the dried mushrooms to convert Ibotenic Acid into Muscimol. (Recipe Below)
		+
		+	If you have picked wild Amanita Muscaria or any similar species the best way to dry them is to place them in an oven on the "warm" setting for several hours.
		+
		+	Amanita Tea:
		+	1. Powder dried mushroom in blender/food processor to maximize surface area.
		+	2. Bring water to just below boiling(Around 2 Cups per 15g). Then add the powdered mushrooms. If you have a thermometer you want to keep the temperature between 180-190°F.
		+	3. Allow mixture to heat for one half to one hour, stirring occasionally. Do not allow the temperature to go above 200°F or you will begin to destroy the Muscimol.
		+	4. Strain away the solid mushroom matter(Cheese cloth works well for this)
		+	5. Add sweetener if you wish as the flavor of the tea is less than desirable.

	== History of usage ==		== History of usage ==

← Older revision		Revision as of 23:35, 6 April 2012
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	== Dosages and consumption methods ==		== Dosages and consumption methods ==
		+	The psychoactive dose of muscimol is around 10–15 mg for a normal person. A correct dose may be difficult to determine because potency varies dramatically from one mushroom to the next.
		+
		+	The dosage information below is for dried Amanita Muscaria only. Other Amanita species, such as Amanita Pantherina, have higher levels of psychoactive compound and dosage should be lowered accordingly.
		+
		+	Light Dose: 1-5g
		+	Common Dose: 5-12g
		+	Strong Dose: 12-30g (Although doses over 15g are not usually recommended because of nausea)
		+
		+	Preparation is key to having an experience as the mushrooms, even when dried, mainly contain Ibotenic Acid, which is far less psychoactive, and more toxic, than Muscimol. Traditionally the mushrooms were eaten and the body would convert most of the ibotenic acid into muscimol in the liver, which would be passed on to the bladder and the urine would be "recycled" to have a psychedelic experience.
		+
		+	It is suggested that a tea be made with the dried mushrooms to convert Ibotenic Acid into Muscimol. (Recipe Below)

	== History of usage ==		== History of usage ==

← Older revision		Revision as of 23:21, 6 April 2012
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	During a test involving rabbits connected to an EEG, muscimol showed a distinctly synchronized EEG tracing. This is substantially different from indolic psychedelics, as brainwave patterns will generally show a desynchronization. In higher doses (2 mg/kg), the EEG will show characteristic spikes.		During a test involving rabbits connected to an EEG, muscimol showed a distinctly synchronized EEG tracing. This is substantially different from indolic psychedelics, as brainwave patterns will generally show a desynchronization. In higher doses (2 mg/kg), the EEG will show characteristic spikes.
−
−	The psychoactive dose of muscimol is around 10–15 mg for a normal person. A Guide to British Psilocybin Mushrooms by Richard Cooper published in 1977 recommends a smaller dose, 8.5 mg, and suggests that it is possible for this amount to be present in as little as 1 g of dried A. muscaria. A correct dose may be difficult to determine because potency varies dramatically from one mushroom to the next.

	Musicmol's LD50 in mice is 3.8 mg/kg s.c, 2.5 mg/kg i.p.		Musicmol's LD50 in mice is 3.8 mg/kg s.c, 2.5 mg/kg i.p.