Gramine - Revision history

Nen888wiki: /* What is gramine */

2024-11-03T12:34:12Z

‎What is gramine

2024-11-03T12:31:54Z

‎Chemical and physical properties

2024-07-15T10:10:56Z

‎What is gramine

2024-05-18T13:37:34Z

2024-05-18T13:35:35Z

‎Extractions

2024-05-18T13:34:21Z

‎Extractions

2024-05-18T13:31:40Z

2024-05-18T13:30:28Z

2024-05-18T13:29:50Z

updated and referenced info on gramine sources and toxicity

2024-05-18T13:28:45Z

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 == What is gramine ==
-* Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects. It is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
+* Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. While it has been previously feared by some to be potentially toxic, recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects. It is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
 == Chemical and physical properties ==

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 == Chemical and physical properties ==
-[Gramine (''3-(dimethylaminomethyl)-indole'') properties http://wiki.dmt-nexus.me/Psychedelic_Compounds_Chemical_and_Physical_Properties#Gramine]
+Gramine (''3-(dimethylaminomethyl)-indole'') properties http://wiki.dmt-nexus.me/Psychedelic_Compounds_Chemical_and_Physical_Properties#Gramine]
 == Extractions ==

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 == What is gramine ==
-* Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects - it is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
+* Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects. It is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
 == Chemical and physical properties ==

@@ Line 6: / Line 6: @@
 == What is gramine ==
-* Gramine is an indole alkaloid present in some plants such as from Phalaris, Phargmites, and Arundo spp. It has been claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects - it is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
+* Gramine is an indole alkaloid present in some plants such as Phalaris, Phargmites, and Arundo spp. It has been previously claimed to be potentially toxic, however recent evidence shows it to have very low toxicity (relative to other alkaloids such as tryptamines) and to have potential antimutagenic effects - it is found most commonly in ''Avena sativa'' (Oats). <ref>''Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays'', Manash Pratim Pathak et al. Drug Chem Toxicol. 2018 Apr. https://pubmed.ncbi.nlm.nih.gov/28523965/ </ref> <ref>https://forum.dmt-nexus.me/threads/phalaris-project.362215/post-3873447</ref>
 == Chemical and physical properties ==

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 == Extractions ==
-Gramine is not soluble in naphtha or petroleum ether. It is soluble in ethanol.
+Gramine is not soluble in naphtha or petroleum ether, therefore extractions using these solvents will not contain gramine. It is soluble in ethanol.
 == Analysis ==