5-MeO-DMT - Revision history

Bringsustogether: /* Effects */

2015-11-04T21:08:14Z

‎Effects

Bringsustogether: /* Effects */

2015-11-04T21:05:19Z

‎Effects

Bringsustogether: /* Effects */

2015-11-04T21:03:48Z

‎Effects

Endlessness: /* Pharmacology, toxicity and general safety */

2011-11-24T02:52:33Z

‎Pharmacology, toxicity and general safety

Endlessness: /* Pharmacology, toxicity and general safety */

2011-11-24T02:52:14Z

‎Pharmacology, toxicity and general safety

Endlessness: /* Chemical and physical properties */

2011-11-16T14:16:10Z

‎Chemical and physical properties

Endlessness: /* Virola spp. */

2011-11-15T16:19:20Z

‎Virola spp.

Endlessness: /* Virola spp. */

2011-11-15T14:49:34Z

‎Virola spp.

Endlessness: /* Life-forms containing 5-MeO-DMT */

2011-11-15T14:35:43Z

‎Life-forms containing 5-MeO-DMT

Endlessness: /* Plants containing 5-MeO-DMT */

2011-11-14T17:40:30Z

‎Plants containing 5-MeO-DMT

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 Higher doses (16-22 mgs smoked) - Body load that hits like a wall of drowning whiteness.  Overwhelming.  No time to resist or submit or feel nauseaus or groan or . . .  Blackout for peak memories.  Weird verbal outbursts or babbling.  Extended peak effects, 20 mins to over an hour. Total time to baseline 2 hours to . . . . extended feeling of not being fully back or integrated that can last days, weeks or months.
-It is worth noting that different anecdotal reports of 5-MeO-DMT use differ significantly in terms of their descriptions of the effects that particular dosages bring on. While some people have reported that 30mg produced only threshold effects, others have been absolutely overtaken by as little as 5mg. This could be due to physical differences between individuals or variations in substance purity.
+It is worth noting that different anecdotal reports of 5-MeO-DMT use differ significantly in terms of their descriptions of the effects that particular dosages bring on. While some people have reported that 30 mgs produces only threshold effects, others have reported being completely overtaken by as little as 5 mgs. These drastic variations could be due to physical differences between individuals or variations in substance purity.
-In order to maximize safety, it is recommended that potential users of 5-MeO-DMT start dosing themselves at the low end of the spectrum (2-6 mgs) before attempting higher dosages. As discussed earlier, even low doses can occasionally produce extremely overwhelming effects.
+In order to maximize safety, it is recommended that potential users of 5-MeO-DMT start dosing themselves at the low end of the spectrum (2-6 mgs) before attempting higher dosages. As discussed earlier, even low doses of 5-MeO-DMT can occasionally produce extremely overwhelming effects.
 == Pharmacology, toxicity and general safety ==

@@ Line 25: / Line 25: @@
 Higher doses (16-22 mgs smoked) - Body load that hits like a wall of drowning whiteness.  Overwhelming.  No time to resist or submit or feel nauseaus or groan or . . .  Blackout for peak memories.  Weird verbal outbursts or babbling.  Extended peak effects, 20 mins to over an hour. Total time to baseline 2 hours to . . . . extended feeling of not being fully back or integrated that can last days, weeks or months.
-It is worth noting that different anecdotal reports of 5-MeO-DMT use differ significantly in terms of their reports of the effect that particular dosages brings on. While some people have reported that 30mg produced only threshold effects, others have been absolutely overtaken by as little as 5mg. This could be due to physical differences between individuals or variations in substance purity.
+It is worth noting that different anecdotal reports of 5-MeO-DMT use differ significantly in terms of their descriptions of the effects that particular dosages bring on. While some people have reported that 30mg produced only threshold effects, others have been absolutely overtaken by as little as 5mg. This could be due to physical differences between individuals or variations in substance purity.
 In order to maximize safety, it is recommended that potential users of 5-MeO-DMT start dosing themselves at the low end of the spectrum (2-6 mgs) before attempting higher dosages. As discussed earlier, even low doses can occasionally produce extremely overwhelming effects.

@@ Line 21: / Line 21: @@
 Lower doses (2-6 mgs smoked) - Crushing body load quickly yielding a sense of body-orgasm.  No CEV's, slight fractal visual distortions with open eyes.  Peak effects 5-25 mins.  Total time to full baseline 1.5-2.0 hours
-Medium doses (7-15 mgs smoked) - Crushing body load yielding gasping and gagging nausea with any resistance and a sort of release into the 5-meo state with surrender - beyond body-orgasm into gasping soul orgasm.  CEV's show a sort of yellow or white field.  Eyes want to open and close.  Open eye visuals are best with living, loved ones.  Fractalized in space and time.  Peak effects 20-40 mins. Total time to full baseline 1.5-2.0 hours.
+Medium doses (7-15 mgs smoked) - Crushing body load yielding gasping and gagging nausea with any resistance and a sort of release into the 5-MeO state with surrender - beyond body-orgasm into gasping soul orgasm.  CEV's show a sort of yellow or white field.  Eyes want to open and close.  Open eye visuals are best with living, loved ones.  Fractalized in space and time.  Peak effects 20-40 mins. Total time to full baseline 1.5-2.0 hours.
 Higher doses (16-22 mgs smoked) - Body load that hits like a wall of drowning whiteness.  Overwhelming.  No time to resist or submit or feel nauseaus or groan or . . .  Blackout for peak memories.  Weird verbal outbursts or babbling.  Extended peak effects, 20 mins to over an hour. Total time to baseline 2 hours to . . . . extended feeling of not being fully back or integrated that can last days, weeks or months.
 == Pharmacology, toxicity and general safety ==

@@ Line 39: / Line 39: @@
 There is some concern regarding taking 5-MeO-DMT orally, specially with a MAOI. There has been at least one reported death (Sklerov, 2005; [http://www.google.com/url?sa=t&rct=j&q=5-meo-dmt%2Bayahuasca%2Bdeath&source=web&cd=7&ved=0CEcQFjAG&url=http%3A%2F%2Fbitnest.ca%2Fexternal.php%3Fid%3D%252506%25257C%252517%25250A6%252504D8EM%25255D%252527%252525%252523%25251B%252506WEW%25251CPIq&ei=qgO5Tp3qL4Wr8AOrzZCsBw&usg=AFQjCNGjI5n62EZtXjYKymYWEUb_YvisUA Callaway 2006]), and some hospitalizations. This might be due to individual metabolic differences. Check [https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=153445#post153445 this] thread for more info. If you are consuming 5-MeO-DMT orally for the first time, specially with MAOIs, start VERY low and raise your dosage gradually.
-General For info on DMT safety, please reffer to [http://wiki.dmt-nexus.me/DMT-Nexus_Wiki:Health_and_Safety Health and Safety]
+General For info on DMT safety, please reffer to [http://wiki.dmt-nexus.me/DMT-Nexus_Wiki:Health_and_Safety Health and Safety] tips regarding set and setting, how to integrate and so on, as written for [[DMT]], are also relevant to 5-MeO-DMT
- tips regarding set and setting, how to integrate and so on, as written for [[DMT]], are also relevant to 5-MeO-DMT
 == Life-forms containing 5-MeO-DMT ==

@@ Line 39: / Line 39: @@
 There is some concern regarding taking 5-MeO-DMT orally, specially with a MAOI. There has been at least one reported death (Sklerov, 2005; [http://www.google.com/url?sa=t&rct=j&q=5-meo-dmt%2Bayahuasca%2Bdeath&source=web&cd=7&ved=0CEcQFjAG&url=http%3A%2F%2Fbitnest.ca%2Fexternal.php%3Fid%3D%252506%25257C%252517%25250A6%252504D8EM%25255D%252527%252525%252523%25251B%252506WEW%25251CPIq&ei=qgO5Tp3qL4Wr8AOrzZCsBw&usg=AFQjCNGjI5n62EZtXjYKymYWEUb_YvisUA Callaway 2006]), and some hospitalizations. This might be due to individual metabolic differences. Check [https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=153445#post153445 this] thread for more info. If you are consuming 5-MeO-DMT orally for the first time, specially with MAOIs, start VERY low and raise your dosage gradually.
-General [[Health and Safety]] tips regarding set and setting, how to integrate and so on, as written for [[DMT]], are also relevant to 5-MeO-DMT
+General For info on DMT safety, please reffer to [http://wiki.dmt-nexus.me/DMT-Nexus_Wiki:Health_and_Safety Health and Safety]
 == Life-forms containing 5-MeO-DMT ==

← Older revision		Revision as of 14:16, 16 November 2011
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	For solubility, melting point, etc, check the [[Psychedelic Compounds Chemical and Physical Properties#5-MeO-DMT\|5-MeO-DMT Chemical and Physical Properties]] WIKI		For solubility, melting point, etc, check the [[Psychedelic Compounds Chemical and Physical Properties#5-MeO-DMT\|5-MeO-DMT Chemical and Physical Properties]] WIKI
		+
		+	5-MeO-DMT can be oxidized naturally or by the use of hydrogen peroxide and becomes [[5-MeO-DMT N-Oxide]]

	== Effects ==		== Effects ==

@@ Line 499: / Line 499: @@
 [[Virola multinerva]]
 * [No.24614; Origin : Manaus, Brazil) - Roots-0.00059% [0.59 mg. of 5-Me0-DMT/ 100 gr dry wt) Agurell et al 1969 ref Trout's Notes.
+* (Schultes No. 24616; Origin Manaus, Brazil] - Trace amounts of 5-MeO-DMT in dry roots. 590ug per 100 grams.  Holmstedt et al. 1980 ref Trout's Notes
-−
-−
 [[Virola peruviana]]
 [[Virola rufula]]
 [[Virola sebifera]]
 [[Virola theiodora]]
 [[Virola venosa]]
 === Humans and other animals ===

@@ Line 482: / Line 482: @@
 [[Virola callophylla]]
 [[Virola calophylloidea]]
 [[Virola elongata]]
 [[Virola multinerva]]
 [[Virola peruviana]]

← Older revision		Revision as of 14:35, 15 November 2011
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	[[Hugonia oreogena]] Schleeter		[[Hugonia oreogena]] Schleeter
	* Traces of 5-MeO-DMT in rootbark. (0.5 mg from 140 grams) (Ikhiri et al. 1987 ref Trout's Notes)		* Traces of 5-MeO-DMT in rootbark. (0.5 mg from 140 grams) (Ikhiri et al. 1987 ref Trout's Notes)
		+
		+	=== Iryanthera spp. ===
		+	[[Iryanthera ulei]]
		+	* Trace amounts in bark Holmstedt et al. 1980