25I-NBOH - Revision history

Ufo: /* Links */

2014-04-19T13:26:59Z

‎Links

Ufo at 13:26, 19 April 2014

2014-04-19T13:26:20Z

Ufo at 13:17, 19 April 2014

2014-04-19T13:17:49Z

Ufo at 13:04, 19 April 2014

2014-04-19T13:04:33Z

Ufo at 13:00, 19 April 2014

2014-04-19T13:00:47Z

Ufo at 13:00, 19 April 2014

2014-04-19T13:00:07Z

Ufo at 12:58, 19 April 2014

2014-04-19T12:58:25Z

Ufo at 12:50, 19 April 2014

2014-04-19T12:50:16Z

Ufo at 12:42, 19 April 2014

2014-04-19T12:42:38Z

Ufo at 12:42, 19 April 2014

2014-04-19T12:42:10Z

@@ Line 25: / Line 25: @@
 ==Links==
 * bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
 * isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
 * wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
 * eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
 == Reference ==

@@ Line 11: / Line 11: @@
 * 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
 * Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
-* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
+* Warning: This chemical is active in the '''[https://en.wikipedia.org/wiki/Microgram microgram (µg)] range'''! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
-* Warning: Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
+* Warning: Do not ingest 25I-NBOH while '''under the influence of a second medicine/substance/drug/MAOI!'''
 * Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
 }}
-'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat the NBOH series substances like the NBOMe series substances.
+'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat 25I-NBOH like you would treat 25I-NBOMe.
 It was discovered in 2006 by a team at Purdue University.
-*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses!
+*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and '''<span style="color:#FF2020">may be fatal in high doses</span>'''!
 *Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

@@ Line 5: / Line 5: @@
 * Open and closed eye visuals, euphoria, change in perception of time
+|
-* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
+* Nausea (possible), [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
+|
-* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
+* paranoia (possible), fear (possible), panic (possible), [https://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
+|
 * 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
 * Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
 * Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
-* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
+* Warning: Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
-* Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [http://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
+* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
 }}
-'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>
+'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat the NBOH series substances like the NBOMe series substances.
 It was discovered in 2006 by a team at Purdue University.
-*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.
+*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses!
 *Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.
 ==Links==

@@ Line 13: / Line 13: @@
 * Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
 * Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
 }}
 '''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

← Older revision		Revision as of 13:00, 19 April 2014
Line 25:		Line 25:

	*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).		*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).
−

	==Links==		==Links==

← Older revision		Revision as of 12:50, 19 April 2014
Line 16:		Line 16:

	It was discovered in 2006 by a team at Purdue University.		It was discovered in 2006 by a team at Purdue University.
		+
		+	*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.
		+
		+	*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.
		+
		+	*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.
		+
		+	*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).
		+

	==Links==		==Links==