1P-ETH-LAD - Revision history

GameComplete at 10:50, 28 January 2016

2016-01-28T10:50:45Z

GameComplete at 10:46, 28 January 2016

2016-01-28T10:46:53Z

GameComplete: /* Links */

2016-01-28T10:41:31Z

‎Links

GameComplete: Created page with "{{Safety_profile | * Psychedelic | * Anecdotal report of being indistinguishable from LSD.[http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-pr..."

2016-01-28T10:36:03Z

Created page with "{{Safety_profile | * Psychedelic | * Anecdotal report of being indistinguishable from LSD.<ref>[http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-pr..."

New page

{{Safety_profile
|
* Psychedelic
|
* Anecdotal report of being indistinguishable from LSD.<ref>[http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-propionyl-lysergic-acid-diethylamide%29-Thread bluelight.org: The Big & Dandy 1P-ETH-LAD (1-propionyl-lysergic acid diethylamide) Thread]</ref>
* Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
|
* Possible side effects: nausea, [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing
|
* Possible mental side effects: paranoia, fear, and panic. Hallucinogen persisting perception disorder.
* No other known specific physical risks at this time.
|
* 1P-ETH-LAD is a research chemical not mentioned in academic literature. The LD50 (median lethal dose) or long term / pharmacological / behavioral risks are not known.
* 1P-ETH-LAD is likely a controlled substance analogue under US law if intended for human consumption.
* This chemical is active in the [https://en.wikipedia.org/wiki/Microgram microgram (µg)] range. Please use caution when working with this substance, a calibrated milligram scale and liquid measurement are vital.
* Do not ingest 1P-ETH-LAD when your mental or physical health is poor. Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting].}}

== Chemical and physical properties ==
[[Image:1P-ETH-LAD.png|right|thumb|200px|1P-ETH-LAD]]
* Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
* Synonym: 1-Propionyl-lysergic acid diethylamide
----

From an old Wikipedia draft regarding 1P-LSD (1P-METH-LAD):<ref>https://en.wikipedia.org/w/index.php?title=Draft:1P-ETH-LAD&oldid=647406505</ref><br />

''Sharing a strong structural similarity with ALD-52, the chemical purportedly used in the 1960's Orange Sunshine 1P-ETH-LAD follows the less common path of modifying the 1- position on the LSD molecule which in the past has been avoided due to unpredictable results or lack of activity.<ref>http://chemistry.mdma.ch/hiveboard/palladium/pdf/Ergot%20-%20The%20Genus%20Claviceps%20(1999)/TF3168ch8.pdf</ref>
''Lots of debate is surrounding the action of 1P-ETH-LAD and is unclear exactly how the chemical is functional with an unconfirmed quote from David E. Nichols believing the chemical should be inactive while most other speculation believing it would simply follow the same metabolic path as ALD-52 and undergo conversion in vivo to LSD.''

''"I am sure that the 1-propionyl would also hydrolyze off of an indole, but I don't know whether in vivo conditions would work. In a chemistry lab, you can get off an N-benzoyl, so an N-propionyl will probably come off too. But in the body? I don't know the answer to that. The compound would not be active as the N-propionyl however. Way that LSD docks into the 5-HT2A receptor, the indole NH hydrogen bonds to serine 5.46. With the propionyl, it won't fit into the receptor."<ref>http://www.shroomery.org/forums/showflat.php/Number/21106929#21106929</ref>''

== Links ==
* [http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-propionyl-lysergic-acid-diethylamide%29-Thread bluelight.org: The Big & Dandy 1P-ETH-LAD (1-propionyl-lysergic acid diethylamide) Thread]
* [https://www.reddit.com/r/Drugs/comments/2s615k/new_novel_lysergamide_1plsd/ reddit.com: New Novel Lysergamide 1P-ETH-LAD]

== References ==
<references />

[[Category:Research Chemicals]]

@@ Line 3: / Line 3: @@
 * Psychedelic
+|
-* Anecdotal report of being comparable to [[AL-LAD]].<ref>[http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot]</ref>
+* Anecdotal report of being comparable to [[AL-LAD]].<ref>http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot</ref>
 * Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
+|
@@ Line 26: / Line 26: @@
 * Square Perforation: 9x9mm
 * Quantity of 1P-ETH-LAD/Square: 100mcg
-From an old Wikipedia draft regarding '''1P-LSD''' (1P-METH-LAD):<ref>https://en.wikipedia.org/w/index.php?title=Draft:1P-ETH-LAD&oldid=647406505</ref><br />
+== Effects ==
 <!--== Brief overview - What is 1P-ETH-LAD? ==
 == Pharmacology, toxicity and general safety ==

@@ Line 3: / Line 3: @@
 * Psychedelic
+|
-* Anecdotal report of being indistinguishable from LSD.<ref>[http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-propionyl-lysergic-acid-diethylamide%29-Thread bluelight.org: The Big & Dandy 1P-ETH-LAD (1-propionyl-lysergic acid diethylamide) Thread]</ref>
+* Anecdotal report of being comparable to [[AL-LAD]].<ref>[http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot]</ref>
 * Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
+|
@@ Line 18: / Line 18: @@
 == Chemical and physical properties ==
 [[Image:1P-ETH-LAD.png|right|thumb|200px|1P-ETH-LAD]]
-* Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
+* Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-ethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
-* Synonym: 1-Propionyl-lysergic acid diethylamide
+* Synonym: 1P-ETH-LAD, 1-propionyl-6-ethyl-6-nor-lysergic acid diethyamide
 ----
-From an old Wikipedia draft regarding 1P-LSD (1P-METH-LAD):<ref>https://en.wikipedia.org/w/index.php?title=Draft:1P-ETH-LAD&oldid=647406505</ref><br />
+From an old Wikipedia draft regarding '''1P-LSD''' (1P-METH-LAD):<ref>https://en.wikipedia.org/w/index.php?title=Draft:1P-ETH-LAD&oldid=647406505</ref><br />
 ''Sharing a strong structural similarity with ALD-52, the chemical purportedly used in the 1960's Orange Sunshine 1P-ETH-LAD follows the less common path of modifying the 1- position on the LSD molecule which in the past has been avoided due to unpredictable results or lack of activity.<ref>http://chemistry.mdma.ch/hiveboard/palladium/pdf/Ergot%20-%20The%20Genus%20Claviceps%20(1999)/TF3168ch8.pdf</ref>
-''Lots of debate is surrounding the action of 1P-ETH-LAD and is unclear exactly how the chemical is functional with an unconfirmed quote from David E. Nichols believing the chemical should be inactive while most other speculation believing it would simply follow the same metabolic path as ALD-52 and undergo conversion in vivo to LSD.''
+''Lots of debate is surrounding the action of 1P-LSD and is unclear exactly how the chemical is functional with an unconfirmed quote from David E. Nichols believing the chemical should be inactive while most other speculation believing it would simply follow the same metabolic path as ALD-52 and undergo conversion in vivo to LSD.''
 ''"I am sure that the 1-propionyl would also hydrolyze off of an indole, but I don't know whether in vivo conditions would work.  In a chemistry lab, you can get off an N-benzoyl, so an N-propionyl will probably come off too.  But in the body?  I don't know the answer to that.  The compound would not be active as the N-propionyl however.  Way that LSD docks into the 5-HT2A receptor, the indole NH hydrogen bonds to serine 5.46.  With the propionyl, it won't fit into the receptor."<ref>http://www.shroomery.org/forums/showflat.php/Number/21106929#21106929</ref>''

@@ Line 42: / Line 42: @@
 == Scientific publications ==-->
 == Links ==
-* [http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-propionyl-lysergic-acid-diethylamide%29-Thread bluelight.org: The Big & Dandy 1P-ETH-LAD (1-propionyl-lysergic acid diethylamide) Thread]
+* [http://www.bluelight.org/vb/threads/781221-Lysergamide-1P-ETH-LAD bluelight.org: Lysergamide: 1P-ETH-LAD]
-* [https://www.reddit.com/r/Drugs/comments/2s615k/new_novel_lysergamide_1plsd/ reddit.com: New Novel Lysergamide 1P-ETH-LAD]
+* [https://www.reddit.com/r/Drugs/comments/4200iw/new_lysergamide_1pethlad/ reddit.com: New lysergamide: 1P-ETH-LAD]
 == References ==